Ceftoren 400 mg (Tablet)
Unit Price: ৳ 250.00 (2 x 4: ৳ 2,000.00)
Strip Price: ৳ 1,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefditoren |
| Company | Aci limited |
| Also available as |
Indications
- Acute Bacterial Exacerbation of Chronic Bronchitis
- Community Acquired Pneumonia
- Pharyngitis
- Tonsillitis
- Uncomplicated Skin and Skin-Structure Infections
Pharmacology
- Broad spectrum third generation cephalosporin antibiotic
- Prodrug hydrolyzed by esterases during absorption
- Bactericidal activity against gram-positive and gram-negative pathogens
- Inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs)
- Stable in the presence of a variety of ß-lactamases
Dosage & Administration
- 400 mg twice daily for 14 days for Community-Acquired Pneumonia
- 400 mg twice daily for 10 days for Acute Exacerbation of Chronic Bronchitis
- 200 mg twice daily for 10 days for Pharyngotonsillitis and Acute Sinusitis
- 200 mg twice daily for 10 days for Uncomplicated Skin and Soft Structure Infections
Interaction
- Reduced oral absorption by Antacids and Famotidine (intravenous administration)
- Increased plasma exposure when co-administered with probenecid
- No effect on the pharmacokinetics of ethinyl estradiol
Contraindications
- Known allergy to the cephalosporin class of antibiotics or any of its components
- Contains sodium caseinate, a milk protein, therefore contraindicated in patients with milk protein hypersensitivity
Side Effects
- Diarrhea
- Nausea
- Headache
- Abdominal pain
- Vaginal moniliasis
- Dyspepsia
- Vomiting
- Abnormal dreams
- Allergic reaction
- Anorexia
- Constipation
- Dizziness
- Dry mouth
- Fever
Pregnancy & Lactation
- Pregnancy category B
- Excreted in breast milk
- Caution should be exercised when used during lactation
Precautions & Warnings
- Not recommended for prolonged antibiotic treatment
- Clinical manifestations of carnitine deficiency reported with prolonged use
- Not recommended in the absence of a proven or strongly suspected bacterial infection
Use in Special Populations
- Not recommended for pediatric patients less than 12 years of age
- No dose adjustments for geriatric patients with normal renal function
- Dose adjustments required for patients with renal insufficiency
- No dose adjustments for patients with mild or moderate hepatic impairment
Overdose Effects
- Adverse effects may include nausea, vomiting, epigastric distress, diarrhea, and convulsions
- Hemodialysis may aid in the removal of Ceftoren from the body
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Keep below 25°C temperature
- Away from light & moisture
- Keep out of the reach of children