Cipro-C 250 mg/5 ml (Powder for Suspension)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ciprofloxacin |
| Company | Chemist laboratories ltd |
| Also available as |
Title
- Cipro-C
Categories
- Medicine
- Antibacterial
- Anti-infective
Description
Cipro-C is indicated for the treatment of single infection or mixed infections caused by two or more susceptible organisms. It can also be used for infections caused by organisms resistant to other antibiotics including Aminoglycosides, Penicillins and Cephalosporins. Cipro-C has a broad spectrum of activity, being active against most gram-negative aerobic bacteria including Enterobacteriaceae and Pseudomonas aeruginosa, as well as gram-positive aerobic bacteria including penicillinase producing, non-penicillinase producing, and methicillin-resistant staphylococci. Cipro-C is available in both oral and IV infusion forms, with a general dosage range for adults of 100-750 mg twice daily depending on the severity and type of infection. The duration of treatment depends upon the severity of infection, clinical response, and bacteriological findings. Cipro-C should be used with caution in patients with suspected or known CNS disorders such as arteriosclerosis or epilepsy and should be kept below 30°C temperature, protected from light and moisture.
Indications
- Treatment of single infection or mixed infections
- Infections resistant to other antibiotics
- Infections of urinary, respiratory, and gastrointestinal tracts
- Gonorrhea and septicaemia
- Severe systemic infections
- Respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
- Gastrointestinal infections
- Infection of the biliary tract
- Intra-abdominal infections
- Bone and joint infection
- Pelvic infections
- Eye, ear, nose, and throat infections
Pharmacology
- Synthetic quinolone anti-infective agent
- Broad spectrum of activity
- Active against gram-negative and gram-positive aerobic bacteria
- Bactericidal action results from interference with enzyme DNA gyrase
- Rapid and well absorption from the G.I. tract
- Widely distributed into body tissues and fluids
- Half-life of about 3.5 hours
- About 30-50% excreted in the urine within 24 hours
Dosage
- Dosage range for adults: 100-750 mg twice daily
- Dosage dependent on severity and type of infection, sensitivity of causative organisms, and patient's age, weight, and renal function
- General duration of treatment: 5-10 days
- Recommended extended-release tablet dose for uncomplicated urinary tract infection: 1000 mg tablet once daily for three days
- Recommended IV infusion doses for various infections
Administration
- Instruction for the use of Ciprofloxacin IV infusion
Interaction
- Avoid concurrent administration with Magnesium or Aluminum containing antacids, sucralfate, or products containing Calcium, Iron, or Zinc
- Avoid concurrent consumption with milk or other dairy products
Contraindications
- Hypersensitivity to Ciprofloxacin or other quinolones
Side Effects
- Gastrointestinal disturbances
- Central nervous system disturbances
- Hypersensitivity reactions
- Joint pain
- Mild photosensitivity
- Transient increase in liver enzymes
- Risk of hypoglycemia and mental health adverse effects
Pregnancy & Lactation
- Not recommended during pregnancy due to potential arthropathy in immature animals
- Not recommended for nursing mothers due to secretion in milk
Precautions & Warnings
- Use with caution in patients with CNS disorders
- Avoid concurrent administration with certain antacids or dairy products
Use in Special Populations
- Not a drug of first choice in pediatric population
Overdose Effects
- May lead to seizures, hallucinations, confusion, abdominal discomfort, renal and hepatic impairment, crystalluria, haematuria, and reversible renal toxicity
Therapeutic Class
- 4-Quinolone preparations
- Anti-diarrhoeal Antimicrobial drugs
Storage Conditions
- Keep below 30°C temperature
- Protect from light and moisture
- Keep out of the reach of children