Ertinib 150 mg (Tablet)

Unit Price: ৳ 700.00 (1 x 10: ৳ 7,000.00)
Strip Price: ৳ 7,000.00

Medicine Details

Category Details
Generic Erlotinib
Company Aristopharma ltd
Also available as
Ertinib 100 mg tablet

Title

  • Erlotinib Tablet

Categories

  • Medicine
  • Oncology
  • Cancer Treatment

Description

  • Oral kinase inhibitor
  • EGFR inhibitor
  • Reversible kinase activity inhibition
  • Chemical name: N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)4-quinazolinamine

Dosage & Administration

  • Recommended daily dose: 150 mg for NSCLC, 100 mg for pancreatic cancer
  • Take on an empty stomach
  • Dose reduction for severe reactions with strong CYP3A4 inhibitors
  • Dose increase for concurrent cigarette smoking or CYP3A4 inducers

Interactions

  • Interaction with coumarin-derived anticoagulants
  • Metabolism by CYP3A4
  • Effects of CYP3A4 inhibitors and inducers on Ertinib exposure
  • Effects of drugs affecting gastric pH on Ertinib exposure

Side Effects

  • Common adverse reactions: rash, diarrhea, anorexia, fatigue, dyspnea, cough, nausea, vomiting
  • Serious adverse reactions: Interstitial Lung Disease (ILD), Renal Failure, Hepatotoxicity, Gastrointestinal Perforation, Bullous and Exfoliative Skin Disorders, Myocardial Infarction/Ischemia, Cerebrovascular Accident, Ocular Disorders, Hemorrhage in Patients Taking Warfarin

Pregnancy & Lactation

  • Pregnancy category D
  • Potential fetal harm
  • Unknown presence in human milk
  • Consideration for discontinuation during nursing

Precautions & Warnings

  • Occurrences of ILD, Renal Failure, Hepatotoxicity, Gastrointestinal Perforations, Bullous and Exfoliative Skin Disorders, Myocardial Infarction/ischemia
  • Monitoring and withholding/discontinuation recommendations for severe reactions

Use in Special Populations

  • Pediatric use not established
  • No overall differences in safety or efficacy for geriatric use

Overdose Effects

  • Tolerated doses in healthy subjects and cancer patients
  • Unacceptable severe adverse reactions above recommended doses
  • Symptomatic treatment for suspected overdose

Therapeutic Class

  • Targeted Cancer Therapy

Storage Conditions

  • Store at temperature not exceeding 30°C
  • Dry place
  • Protection from light and moisture

Related Brands