Toramax 60 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 190.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Popular pharmaceuticals ltd
Also available as
Toramax 10 mg tablet Toramax 30 mg injection Lopadol 05 eye drop

Indications

  • Short-term management of moderate to severe acute post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decrease in eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
  • Inhibits prostaglandin synthesis as a peripherally acting analgesic
  • Pharmacokinetic property is linear
  • Highly protein bound and largely metabolized in the liver
  • Excretion occurs in the urine

Pharmacology

  • Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
  • Acts by inhibiting the cyclooxygenase enzyme system and hence inhibits prostaglandin synthesis
  • Demonstrates minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Tablet recommended dose is 10 mg every 4-6 hours for short-term use up to 7 days
  • Injection for moderately severe, acute pain
  • Single or multiple doses, on a regular or as-needed schedule
  • Administration guidelines for different age groups and conditions
  • Eye Drops usage instructions for adults

Interaction

  • Other NSAIDs or aspirin increase side effects
  • Anti-coagulants enhance anti-coagulant effect
  • Beta Blockers reduce anti-hypertensive effect
  • ACE Inhibitors increase risk of renal impairment
  • Methotrexate enhances toxicity of methotrexate

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Children under 16 years of age
  • Prophylactic analgesic use before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melena
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

  • Pregnancy category C
  • Should be avoided in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Caution in patients over 65 years
  • Caution in patients with active or suspected peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
  • Specific caution for use of eye drops in patients with corneal epithelial breakdown and wearing contact lenses

Therapeutic Class

  • Rheumatoid Arthritis drugs
  • Non-Opioid Analgesics

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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