Orbuten 400 mg (Capsule)
Unit Price: ৳ 120.00 (1 x 10: ৳ 1,200.00)
Strip Price: ৳ 1,200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftibuten dihydrate |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Treatment of acute bacterial exacerbations of chronic bronchitis
- Treatment of acute bacterial otitis media
- Treatment of pharyngitis and tonsillitis
Pharmacology
- Semi-synthetic Cephalosporin antibiotic for oral administration
- Bactericidal action by binding to essential target proteins of the bacterial cell wall
Dosage & Administration
- Adult dosage for otitis media: 400 mg orally every 24 hours for 10 days
- Pediatric dosage for cystitis: >12 years: 400 mg orally every 24 hours for 7 days
Interaction
- Theophylline & antacid do not alter the pharmacokinetic profile of Orbuten
- Ranitidine increases the Cmax & AUC of Orbuten
Contraindications
- Contraindicated in patients with known allergy to the cephalosporin group of antibiotics
Side Effects
- Nausea
- Headache
- Diarrhea
- Dyspepsia
- Dizziness
- Abdominal pain
- Vomiting
Pregnancy & Lactation
- Pregnancy Category B
- Caution should be exercised when Ceftibuten is administered to nursing women
Precautions & Warnings
- Prolonged treatment may result in the possible emergence and overgrowth of resistant organisms
- Dose may require adjustment in patients with varying degrees of renal insufficiency
Use in Special Populations
- Dosage adjustment in patients with renal impairment
- No dose adjustment necessary for patients with hepatic impairment
Therapeutic Class
- Third generation Cephalosporins
Reconstitution
- Reconstitution process using purified water and granules
- Prepared suspension to be consumed within 14 days of preparation if kept in a refrigerator
Storage Conditions
- Store below 25°C, protected from light and moisture
- Suspension may be used for 14 days after reconstitution if stored at 2°C to 8°C