Cinamycin 600 mg/4 ml (IM/IV Injection)

4 ml ampoule: ৳ 70.00 (1 x 5: ৳ 350.00)

Medicine Details

Indications

  • Upper respiratory infections
  • Lower respiratory infections
  • Skin and soft tissue infections
  • Bone and joint infections
  • Pelvic infections
  • Intra-abdominal infections
  • Septicemia and endocarditis
  • Dental infections
  • Multi-drug resistant Plasmodium falciporum infection

Description

  • Lincosamide antibiotic
  • Derived from lincomycin
  • Effective against aerobic gram-positive cocci
  • Effective against anaerobic gram-negative bacilli
  • Effective against anaerobic gram-positive non-spore forming bacilli
  • Effective against anaerobic and microaerophilic gram-positive cocci

Dosage & Administration

  • Dosage for Clindamycin Capsule: 150-300 mg every six hours for serious infections
  • Dosage for Clindamycin Powder for oral solution: 8-25 mg/kg/day divided into 3 or 4 equal doses
  • Dosage for Clindamycin IV/IM Injection: Adult dosage of 600-4800 mg/day in 2-4 equal doses
  • Dosage for neonates: 15-20 mg/kg/day in 3-4 equal doses
  • Dosage for pediatric patients: 20-40 mg/kg/day in 3-4 equal doses

Interaction

  • Enhances the action of other neuromuscular blocking agents
  • Antagonism with erythromycin in vitro

Contraindications

  • Hypersensitivity to clindamycin or any ingredients

Side Effects

  • Abdominal pain
  • Oesophagitis and oesophagial ulcer
  • Nausea
  • Vomiting and diarrhea
  • Pruritus
  • Skin rashes
  • Urticaria

Pregnancy & Lactation

  • Pregnancy Category B
  • Crosses the placenta
  • Appears in breast milk

Precautions & Warnings

  • Caution in individuals with a history of gastrointestinal disease, particularly colitis

Use in Special Populations

  • Monitoring of organ system functions desirable for newborns and infants
  • No dose adjustment necessary for geriatric use

Overdose Effects

  • Expect adverse reactions similar to normal doses
  • Haemodialysis and peritoneal dialysis not effective in removing Cinamycin from serum
  • Treat with simple gastric lavage
  • No specific antidote known

Therapeutic Class

  • Macrolides

Reconstitution

  • Direction for reconstitution of powder for oral solution
  • Direction for dilution of Cinamycin injection for intravenous use
  • Physico-Chemical Stability of diluted solutions of Clindacin Injection

Storage Conditions

  • Below 30°C temperature
  • Away from light & moisture
  • Keep out of reach of children

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