Eltropag 25 mg (Tablet)
Unit Price: ৳ 500.00 (1 x 10: ৳ 5,000.00)
Strip Price: ৳ 5,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Eltrombopag olamine |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of thrombocytopenia in patients with persistent or chronic immune thrombocytopenia
- Treatment of thrombocytopenia in patients with hepatitis C infection
- Treatment of severe aplastic anemia
Pharmacology
- Thrombopoietin (TPO) receptor agonist
- Interacts with the transmembrane domain of the human TPO-receptor
- Induces proliferation and differentiation from bone marrow progenitor cells
Dosage & Administration
- Oral route of administration
- Can be taken with or without a meal low in calcium
- Specific dosing for different conditions and patient groups
Interaction
- Drug interaction with medication (polyvalent cations)
- Drug interaction with food (calcium rich foods)
Contraindications
- Known hypersensitivity to eltrombopag or any components
Side Effects
- Common side effects include anemia, nausea, pyrexia, ALT increased, cough, fatigue, headache, and diarrhea
Pregnancy & Lactation
- Insufficient data for assessing drug-associated risks
- No data on presence in human milk or effects on the breastfed child
Precautions & Warnings
- Increased risk of hepatic decompensation in patients with chronic hepatitis C
- Increased risk of death and progression of myelodysplastic syndromes to acute myeloid leukemia
- Portal vein thrombosis reported in patients with chronic liver disease receiving eltrombopag
Use in Special Populations
- Safety and efficacy not established in pediatric patients below the age of 1 year
- Safety and efficacy not established in pediatric patients with thrombocytopenia associated with chronic hepatitis C and refractory severe aplastic anemia
Overdose Effects
- Excessive increase in platelet counts leading to thrombotic or thromboembolic complications
- Consider oral administration of metal cation containing preparation in case of overdose
Therapeutic Class
- Haemostatic drugs
Storage Conditions
- Store in a cool and dry place below 25°C
- Protect from light
- Keep away from the reach of children