Orizone 2 gm/vial (IV Injection)
2 gm vial: ৳ 501.50 (5's pack: ৳ 2,507.50)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Pharmacil limited |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity against Gram-positive and Gram-negative organisms
- Interferes with bacterial cell wall synthesis
- High stability in the presence of beta lactamases
- Relatively long plasma elimination half-life of about 6 to 9 hours
Dosage
- Usual dose for adults: 1 to 2 gm IV or IM once a day or twice a day
- Maximum dose for adults: 4 gm/day
- Usual dose for infants and children: 50 to 75 mg/kg IV or IM once a day or twice a day
- Maximum dose for infants and children: 2 gm/day
- Duration of therapy: 4 to 14 days
Administration
- Intramuscular or Intravenous administration
- Preparation of solutions for injections
- Injection should be administered over 2-4 minutes
- Patient tolerance test recommended before starting treatment
- Freshly reconstituted solution recommended for injections
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastrointestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Not established safety in human pregnancy
- Caution advised during lactation
Precautions & Warnings
- Risk of anaphylactic shock
- Rare cases of gallbladder sludge detected by sonograms
- Regular blood picture checks during prolonged treatment
Use in Special Populations
- Not recommended for neonates if premature or newborn
Overdose Effects
- No specific antidote
- Symptomatic treatment recommended
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30°C)
- Keep away from light & moisture
- Keep out of the reach of children