Telmidip 5 mg+40 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate telmisartan |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
- May be used as initial therapy
- Blood pressure goals
Pharmacology
- Fixed dose combination of Telmisartan and Amiodipine
- Angiotensin II antagonist
- Vasoconstriction
- Renin-angiotensin system effects
- Aldosterone-secreting effects
- Calcium-channel blocker
- Vasodilator
- Reduction in blood pressure
Dosage & Administration
- Usual starting dose of 40/5 mg once daily
- 80/5 mg once daily option for larger blood pressure reductions
- 40/5 mg tablets for patients not adequately controlled
- Individualized dosage
- Maximum recommended dose of 80/10 mg once daily
Interaction
- No clinically significant interaction with specific drugs
- Inhibition of CYP2C19 by Telmisartan
- Safe administration with various drugs
Contraindications
- Hypersensitivity to the product or its components
- Pregnancy & lactation
- Biliary obstructive disorders
- Severe hepatic impairment
- Hypotension
- Cardiogenic shock
- Left ventricle outflow tract obstruction
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Hypotension
- Cough
- Abdominal pain
- Diarrhea
- Nausea
- Pruritus
- Myalgia
- Chest pain
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C and D
- Excretion in human milk
- Adverse effects on nursing infant
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct volume or salt depletion for hypotension
- Titrate slowly in hepatic or severe renal impairment
- Monitor for worsening heart failure
- Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker
- Risk of precipitating myocardial infarction
Use in Special Populations
- Pediatric use not established
- Initial therapy not recommended for patients ≥75 years old
- Initial therapy not recommended for hepatically impaired patients
Overdose Effects
- Manifestations of overdosage
- Symptomatic hypotension
- Supportive treatment
- Excessive peripheral vasodilation
- Reflex tachycardia
- Cardiac and respiratory monitoring
- Elevation of extremities
- Administration of fluids
- Administration of vasopressors
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children