Parten 50 mg (Tablet)
Unit Price: ৳ 5.03 (3 x 10: ৳ 150.90)
Strip Price: ৳ 50.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Losartan potassium |
| Company | Jayson pharmaceuticals ltd |
Indications
- Hypertension
- Renal Protection in Type-2 Diabetic Patients with Proteinuria
Pharmacology
- Non-peptide orally active angiotensin II receptor blocker
- Reduces vasoconstriction and aldosterone release
Dosage & Administration
- Usual starting and maintenance dose of 50 mg once daily
- Total daily dose ranges from 25 mg to 100 mg
- Lower starting dose of 25 mg once daily for patients over 75 years
Interaction
- Reduction in active metabolite levels with Rifampicin and fluconazole
- Potentiation of antihypertensive effects with hydrochlorothiazide
- Increase in serum potassium with potassium-sparing diuretics
- Attenuation of antihypertensive effect by indomethacin
- Increased risk of renal impairment with certain drug combinations
Contraindications
- Pregnant women
- Hypersensitivity to any component of the product
- Concurrent use with Aliskiren in patients with diabetes
Side Effects
- Dizziness
- Diarrhea
- Nasal congestion
- Cough
- Upper respiratory infection
- Fatigue
- Oedema
- Abdominal pain
- Chest pain
- Nausea
- Headache
- Pharyngitis
Pregnancy & Lactation
- Pregnancy Category D
- Potential excretion in human milk
- Decision making regarding nursing versus drug continuation
Precautions & Warnings
- Reduced fetal renal function and increased fetal and neonatal morbidity and death in second and third trimesters of pregnancy
- Risk of symptomatic hypotension in intravascularly volume-depleted patients
- Significant increase in plasma concentration in cirrhotic patients
- Changes in renal function including renal failure in renal impaired patients
Use in Special Populations
- No initial dosage adjustment for patients with mild renal impairment
- Lower starting dose for moderate to severe renal impairment or patients on dialysis
- Lower dose consideration for patients with hepatic impairment
- Use with caution in patients with intravascular volume depletion
Therapeutic Class
- Angiotensin-II receptor blocker
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children