Bakticef 500 mg/vial (IM Injection)
500 mg vial: ৳ 155.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Osl pharma limited |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity against Gram-positive and Gram-negative organisms
- Interferes with bacterial cell wall synthesis
- High stability in the presence of beta lactamases
- Long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Excretion in urine and bile
- High protein binding (95%)
Dosage
- Usual adult dose of 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose of 4 gm/day
- Usual infant and child dose of 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum infant and child dose of 2 gm/day
- Duration of therapy for more than 2 days after signs and symptoms of infection have disappeared
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections
- Administration over 2-4 minutes for intramuscular or intravenous injection
- Administration over 30 minutes for tubing infusion
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects including diarrhea, nausea, vomiting, stomatitis, and glossitis
- Cutaneous reactions including rash, pruritus, urticaria, edema, and erythema multiforme
- Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia, anemia, and neutropenia
- Hepatic reactions including elevations of SGOT or SGPT, bilirubinemia
- CNS reactions including nervousness, confusion, sleep disturbances, headache, hyperactivity, convulsion, hypertonia, and dizziness
- Rare occurrence of local phlebitis following intravenous administration
Pregnancy & Lactation
- Unsafe in pregnancy, caution in lactation
Precautions & Warnings
- Risk of anaphylactic shock
- Detection of gallbladder sludge in rare cases
- Regular blood picture check during prolonged treatment
Use in Special Populations
- Not for premature and newborn neonates up to 28 days of age
Overdose Effects
- No specific antidote, treatment should be symptomatic
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store below 30°C, away from light & moisture, Keep out of reach of children