Duxol 0.05% (Ophthalmic Emulsion)
5 ml drop: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Difluprednate |
| Company | Osl pharma limited |
Indications
- Treatment of inflammation
- Pain relief after ocular surgery
- Uveitis treatment
- Treatment of pseudophakic cystoid macular edema
- Management of ocular surface diseases like blepharitis and corneal inflammation
Pharmacology
- Inhibition of inflammatory response
- Delayed or slowed healing
- Inhibition of edema
- Capillary dilation suppression
- Leukocyte migration inhibition
- Fibroblast proliferation control
- Collagen deposition regulation
- Scar formation suppression
- Mechanism of action of ocular corticosteroids
- Induction of phospholipase A2 inhibitory proteins
Dosage & Administration
- Dosage for inflammation and pain post ocular surgery
- Duration of treatment after surgery
- Dosage for uveitis treatment
- Tapering according to clinical response
- Dosage for blepharitis treatment
- Frequency and duration of treatment for pseudophakic cystoid macular edema
Interaction
- Lack of specific drug interaction studies
Contraindications
- Contradiction with active viral diseases
- Contraindication with mycobacterial infection
- Contraindication with fungal diseases of ocular structures
Side Effects
- Elevated intraocular pressure
- Optic nerve damage risk
- Visual acuity and field defects
- Posterior subcapsular cataract formation
- Secondary ocular infection risk
- Corneal and conjunctival adverse reactions
- Eye pain and photophobia
- Anterior chamber cells and flare
- Blepharitis potential
Pregnancy & Lactation
- Pregnancy Category C
- Embryotoxic and teratogenic potential
- Use during pregnancy and potential risks
- Presence in breast milk and caution in nursing mothers
Precautions & Warnings
- Glaucoma risk with prolonged use
- Posterior subcapsular cataract formation risk with prolonged use
- Caution with herpes simplex history
- Fungal infection risk
- Contamination prevention
Use in Special Populations
- Pediatric use for inflammation after cataract surgery
- Safety comparison between Duxol and Prednisolone Acetate
- Geriatric safety and effectiveness
Overdose Effects
- Lack of acute problems
- Dilution advice if accidentally ingested
Therapeutic Class
- Belongs to ophthalmic steroid preparations
Storage Conditions
- Room temperature storage
- Protection from light and freezing
- Usage duration after first bottle opening