Exilok 40 mg/vial (IV Injection)

40 mg vial: ৳ 100.00

Medicine Details

Category Details
Generic Esomeprazole
Company Osl pharma limited
Also available as
Exilok 20 mg capsule Exilok 40 mg capsule Exilok 20 mg tablet Exilok 40 mg tablet

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Enteric-coated pellet formulation
  • Specific inhibition of H+/K+-ATPase
  • Better acid control than racemic proton pump inhibitors
  • Absorption peak at approximately 1.5 hours
  • Metabolized in the liver by CYP enzyme system

Dosage

  • Multiple dosage forms - oral, IV injection, IV infusion
  • Different dosages for different indications
  • Oral administration should be at least one hour before meals
  • Duration of treatment for each indication

Administration

  • Tablet or capsule should be swallowed whole
  • Oral suspension should be taken into a small glass containing water
  • IV injection solution preparation and administration

Interaction

  • Metabolized by CYP2C19 and CYP3A4
  • Inhibition of gastric acid secretion
  • Potential interference with drug absorption due to gastric pH
  • No clinically significant interactions with certain drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions warnings

  • Symptomatic response does not preclude gastric malignancy
  • Guidance for patients with difficulty swallowing capsules
  • Use of antacids while taking Exilok

Special populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy between elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • No alteration in pharmacokinetics in renal impairment

Overdose effects

  • Lethality in rats at high doses
  • Signs of acute toxicity
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage conditions

  • Store at a temperature not exceeding 30°C
  • Dry place, protect from light and moisture
  • Keep out of reach of children

Chemical structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure: Image provided

Commonly asked questions

  • What is Exilok 40 mg/vial Injection?
  • What is Exilok 40 mg/vial Injection used for?
  • Side effects of Exilok 40 mg/vial Injection
  • Use of Exilok 40 mg/vial Injection during pregnancy or breastfeeding
  • Duration for Exilok 40 mg/vial Injection to work
  • Quick tips for using Exilok 40 mg/vial Injection

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