Tobracin D 0.1%+0.3% (Ophthalmic Solution)
5 ml drop: ৳ 150.45
Medicine Details
| Category | Details |
|---|---|
| Generic | Dexamethasone tobramycin |
| Company | Osl pharma limited |
| Also available as |
Indications
- Steroid responsive inflammatory ocular conditions
- Chronic anterior uveitis
- Corneal injury from chemical, radiation, or thermal burns
- Penetration of foreign bodies
Pharmacology
- Bactericidal activity of Tobramycin
- Inhibition of protein synthesis by Dexamethasone
- Anti-inflammatory activity of Dexamethasone
Dosage & Administration
- Eye Drops: 3-5 times per day initially, may increase to every 2 hours
- Eye Ointment: 3-4 times per day
- Pediatric use not established below 2 years
Interaction
- No specific interaction studies with Tobracin D eye drops
- Allow 10 minutes between successive applications with other topical ophthalmic medicines
Contraindications
- Epithelial herpes simplex keratitis
- Vaccinia
- Varicella
- Mycobacterial infection of the eye
- Hypersensitivity to any component
Side Effects
- Hypersensitivity
- Localized ocular toxicity
- Elevation of intraocular pressure
- Optic nerve damage
- Posterior subcapsular cataract formation
- Delayed wound healing
Pregnancy & Lactation
- Limited studies in pregnant women
- Use during pregnancy justified if benefit outweighs risk
- Caution during nursing due to potential systemic absorption
Precautions & Warnings
- Consider fungal infections after long-term steroid dosing
- Prolonged use may result in overgrowth of non-susceptible organisms
- Cross-sensitivity to other aminoglycoside antibiotics
- Appropriate therapy if superinfection occurs
Overdose Effects
- No known overdose effects through local administration
- In case of accidental oral intake, take measures to reduce resorption
- No specific antidote
Therapeutic Class
- Ophthalmic steroid - antibiotic combined preparations
Storage Conditions
- Store at room temperature
- Close bottle immediately after use
- Do not use for longer than one month after opening