Orlev 500 mg (Tablet)
Unit Price: ৳ 15.10 (2 x 10: ৳ 302.00)
Strip Price: ৳ 151.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levofloxacin hemihydrate |
| Company | Orion pharma ltd |
Product Title
- Orlev Broad-Spectrum Antibacterial Agent
Categories
- Medicine
- Pharmaceuticals
- Antibiotics
Description
- Synthetic, broad-spectrum, third-generation fluoroquinolone derivative for oral administration
Pharmacology
- Inhibits bacterial topoisomerase IV and DNA gyrase
- Exerts antibacterial action
- Active against a wide range of microorganisms
Dosage
- Available in 250mg, 500mg, 750mg tablets
- Oral solution should be taken 1 hour before or 2 hours after eating
- Injection administered by intravenous infusion
- Dosage varies for different infections and age groups
Administration
- Instructions for the use of Levofloxacin Infusion
- Check container for leaks or precipitates before use
- Regulate rate of administration with flow control clamp
Interaction
- Avoid co-administration with solutions containing multivalent cations
- Reduced absorption with antacids, iron, and adsorbents
- Increased risk of CNS stimulation with NSAIDs
- Increased risk of bleeding with warfarin
Contraindications
- Hypersensitivity to levofloxacin or quinolone antimicrobial agents
Side Effects
- Risk of retinal detachment
- Nausea, vomiting, diarrhea, abdominal pain, flatulence
- Rare occurrence of phototoxicity
- Rarely tremors, depression, anxiety, confusion
Pregnancy & Lactation
- Not recommended during pregnancy or nursing
- Effects on unborn child or nursing infant are unknown
Precautions & Warnings
- Administer by slow intravenous infusion
- Maintain adequate hydration during administration
- Daily amount of water intake should be sufficient to avoid concentrated urine
Overdose Effects
- Low potential for acute toxicity
- Empty stomach in case of acute overdose
- Maintain appropriate hydration
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light and moisture
- Keep out of the reach of children
Indications
- Treatment of mild, moderate, and severe infections caused by susceptible microorganisms
Usability Features
- Oral administration
- Intravenous infusion
- Suitable for sequential therapy (intravenous to oral)
Material
- Chiral fluorinated carboxyquinolone
Technical Specifications
- Available in 250mg, 500mg, 750mg doses
- In vitro activity against a wide range of microorganisms
Design Elements
- Broad-spectrum antibiotic
- Chiral fluorinated carboxyquinolone derivative
Color Options
- Not applicable
Dimensions
- Various tablet sizes available
Functions
- Antibacterial agent
- Inhibits DNA replication, transcription, repair, and recombination
Warnings
- Avoid use if solution is cloudy or if a precipitate is present
Age Group
- Dose variation for children and adults
Instructions
- Dosage without regard to food for tablets
- Dosage before or after eating for oral solution
Infections Treated
- Acute maxillary sinusitis
- Acute bacterial exacerbation of chronic bronchitis
- Community-acquired pneumonia
- Uncomplicated & complicated urinary tract infections
- Acute pyelonephritis
- Uncomplicated & complicated skin and soft tissue infections
- Enteric infections
Related Compounds
- Third-generation fluoroquinolone
- Levofloxacin
Infusion
- Regulate rate of administration with flow control clamp
Storage
- Below 30°C temperature
- Away from light and moisture
Additives
- Not to be added to Levofloxacin Injection or infused simultaneously through the same intravenous line
Dosage Recommendations
- Specific dosages for various infections and age groups
- Possibility of sequential therapy
Adverse Reactions
- Nausea, vomiting, diarrhea, rare occurrence of phototoxicity
- Rarely tremors, depression, anxiety, confusion
Toxicity
- Low potential for acute toxicity
- Appropriate hydration maintenance
Complications
- Retinal detachment
- CNS stimulation with NSAIDs
- Increased risk of bleeding with warfarin
Handling Instructions
- Check for leaks or precipitates before use
- Regulate rate of administration with flow control clamp
Avoidance
- Co-administration with solutions containing multivalent cations
- Reduced absorption with antacids, iron, and adsorbents