Xclor 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 190.57
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefaclor monohydrate |
| Company | Orion pharma ltd |
Indications
- Treatment of respiratory tract infections
- Treatment of otitis media
- Treatment of pharyngitis and tonsillitis
- Treatment of urinary tract infections
- Treatment of skin and skin structure infections
Pharmacology
- Second generation cephalosporin antibiotic
- Activity against alpha and beta haemolytic streptococci
- Activity against staphylococci
- Activity against Streptococcus pneumoniae
- Activity against Escherichia coli
- Activity against Klebsiella species
- Has stability against b-lactamase inactivation
Dosage & Administration
- Usual adult dose of 250 mg every 8 hours
- Maximum adult dosage of 4 g/day
- Usual pediatric dose of 20 mg/kg/day in divided doses every 8 hours
- Maximum pediatric dosage of 1 g/day
- Dosage adjustments in renal impairment
- Dosage considerations for patients undergoing haemodialysis
- Geriatric use considerations
Interaction
- Potential false-positive reaction for glucose in urine
- Possible interaction with oral anticoagulants
- Monitoring of prothrombin time recommended
- Possible increased anticoagulant effect
Contraindications
- Contraindicated in patients with known allergy to cephalosporin group of antibiotics
Side Effects
- Gastro-intestinal symptoms including diarrhea, nausea, and vomiting
- Occasional reports of transient hepatitis and cholestatic jaundice
- Potential occurrence of fever, abdominal pain, and superinfection
- Rare cases of renal dysfunction, toxic nephropathy, and hemorrhage
Pregnancy & Lactation
- Limited data in pregnant women
- Caution advised for use during pregnancy
- Detection of small amounts in mother's milk
- Unknown effect on nursing infants
Precautions & Warnings
- Avoid use in absence of proven or strongly suspected bacterial infection
- Risk of development of drug-resistant bacteria
- Possibility of overgrowth of nonsusceptible organisms with prolonged use
- Inhibition of renal excretion by Probenecid
- Caution in individuals with a history of gastrointestinal disease
- Careful inquiry about previous hypersensitivity reactions to cephalosporins and penicillins
Overdose Effects
- Potential symptoms of nausea, vomiting, epigastric distress, and diarrhea
Therapeutic Class
- Belongs to second generation Cephalosporins
Reconstitution
- Instructions for reconstituting powder for suspension
- Instructions for reconstituting pediatric drops
Storage Conditions
- Recommendations for storage at room temperature
- Guidelines for storage after reconstitution