Cildocal 10 mg (Tablet)

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Cilnidipine
Company Delta pharma ltd
Also available as

Indications

  • Management of hypertension for end-organ protection
  • Useful in elderly patients and those with diabetes and albuminuria
  • Increasingly used in patients with chronic kidney disease

Pharmacology

  • Dihydropyridine calcium-channel blocker
  • Binds to L-type voltage dependent calcium channel
  • Inhibits Ca2+ influx in vascular smooth muscle cells
  • Causes vasodilation
  • Inhibits Ca2+ influx via N-type voltage dependent calcium channels
  • Suppresses reflex increase in heart rate after blood pressure reduction

Dosage & Administration

  • Adult dose: 5-10 mg once daily after breakfast
  • Maximum adult dose: 20 mg once daily
  • Pediatric use safety not established
  • Lowest possible dose (5 mg) for elderly patients

Interaction

  • Interacts with other antihypertensive medications
  • Interacts with antipsychotics causing hypotension
  • Interacts with quinidine, carbamazepine, phenytoin, rifampicin, cimetidine, erythromycin

Contraindications

  • Contraindicated in patients with known sensitivity to Cilnidipine or any excipients
  • Contraindicated in patients with cardiogenic shock, recent MI, acute unstable angina, and severe aortic stenosis

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Palpitations
  • GI disturbances
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Depression

Pregnancy & Lactation

  • Should not be administered in pregnant or possibly pregnant women
  • Should be avoided in nursing mothers
  • Discontinue lactation if administration is indispensable

Precautions & Warnings

  • Administer with care in patients with serious hepatic dysfunction
  • Administer with care in patients with history of serious adverse reactions to calcium antagonists
  • Gradually decrease dosage during discontinuation under close observation

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep away from reach of children

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