Lonapam 1 mg (Tablet)

Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00

Medicine Details

Title

Lonapam 1mg Tablet

Categories

  • Medication
  • Anticonvulsant
  • Anxiolytic

Description

Lonapam 1mg Tablet is indicated for the treatment of panic disorder, with or without agoraphobia, and as an adjunct in the treatment of Lennox-Gastaut Syndrome (petit mal variant) and other seizures.

Dimensions

N/A

Color options

  • N/A

Functions

  • Anticonvulsant
  • Sedative
  • Anxiolytic
  • Muscle Relaxant

Materials

  • N/A

Technical specifications

  • Molecular Formula: C15H10ClN3O3
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-284-clonazepam-chemical-structure-S6GmKrvYS03ZYjOTAtig.svg

Design elements

  • Tablet

Usability features

  • Long-term control of panic disorder
  • Control of seizures

Dosage

  • Oral:
    • Adults:
      • Initial dose for seizure disorders should not exceed 1.5mg/day
      • Initial dose for panic disorder is 0.25mg given in two divided doses
    • Pediatric Patients: Initial dose for infants and children should be between 0.01 and 0.03mg/kg/day
  • Injection:
    • Infants and children: Half of a vial (0.5mg)
    • Adults: 1 vial (1mg) by slow IV injection or by IV infusion

Interaction

Lonapam does not alter the pharmacokinetics of certain drugs, but its effect on the metabolism of other drugs has not been investigated.

Contraindications

  • Hypersensitivity to benzodiazepines
  • Significant liver disease
  • Acute narrow angle glaucoma

Side effects

  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Coma
  • Tremor
  • Vertigo
  • Depression
  • Hallucinations
  • Increased libido
  • Insomnia
  • Psychosis
  • Palpitations

Pregnancy and lactation

  • Pregnancy: Administered to pregnant women if the potential benefits outweigh the risk to the fetus
  • Nursing Mothers: Mothers undergoing treatment with this drug should not breastfeed

Precautions and warnings

  • May increase the incidence of generalized tonic-clonic seizures
  • Concomitant use with valproic acid may produce absence status

Special populations

  • Pediatric Use: Caution required in infants and small children
  • Geriatric Use: Pharmacologic effects appear to be greater in elderly patients
  • Renal Impairment: No dose adjustment is required
  • Hepatic Impairment: Plasma protein binding is significantly different in cirrhotic patients

Overdose effects

  • Symptoms:
    • Drowsiness
    • Ataxia
    • Coma
    • Hypotension
    • Respiratory depression
    • Increased frequency of seizures
  • Treatment: Monitor vital signs and institute supportive measures, consider the use of flumazenil if severe CNS depression

Therapeutic class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Slow intravenous injection: The contents of the vial must be diluted with 1 ml of water for injection prior to administration
  • Intravenous infusion: Lonapam can be diluted for infusion in a ratio of 1 vial (1 mg) to at least 85 ml diluting media
  • Intramuscular injection: To be used only in exceptional cases or if IV administration is not feasible

Storage conditions

Keep in a dry place away from light and heat

Compound summary

  • Molecular Formula: C15H10ClN3O3
  • Chemical Structure: https://medex.com.bd/storage/res/g-res-284-clonazepam-chemical-structure-S6GmKrvYS03ZYjOTAtig.svg

Commonly asked questions

  • Is Lonapam a sleeping pill?
  • Can it be taken for the longer-term?
  • What kind of withdrawal symptoms occur on stopping?
  • How to look for early symptoms of suicidal thoughts?
  • Does it cause weight gain?
  • Can it affect memory?
  • Can it be harmful if more than recommended doses are used?
  • Can it be taken with other medications like zolpidem and quetiapine?

Quick tips

  • The addiction potential of Lonapam is very high
  • May cause dizziness, avoid operating machinery
  • Avoid consuming alcohol
  • Inform the doctor if pregnant or planning to conceive
  • Do not stop taking suddenly without doctor's advice

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