Atostin 10 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Somatec pharmaceuticals ltd
Also available as
Atostin 20 mg tablet

Title

  • Atostin 10 mg Tablet

Categories

  • Medication
  • Pharmaceuticals

Description

  • Atostin 10 mg Tablet is a selective inhibitor of HMG-CoA reductase used to reduce elevated cholesterol and triglycerides levels in various diseases.

Dosage form

  • Tablet

Size

10 mg

Pharmacological class

  • HMG-CoA Reductase Inhibitor

Therapeutic class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Active ingredient

  • Atorvastatin

Indications

  • Reduction of total cholesterol and LDL cholesterol in patients with heterozygous and homozygous familial hypercholesterolaemia
  • Reduction of elevated cholesterol and triglycerides in patient with mixed dyslipidemia (Fredrickson Type Ia and Ib)
  • Treatment of patients with elevated serum triglyceride levels in hypertriglyceridaemia (Fredrickson Type IV)
  • Treatment of patients with dysbetalipoproteinaemia (Fredrickson Type III)
  • Reduction of cardiac ischaemic events in patients with asymptomatic or mild to moderate symptomatic coronary artery disease with elevated LDL-cholesterol level
  • Reduction of total and LDL-cholesterol concentrations patients with hypercholesterolemia associated with or exacerbated by diabetes mellitus or renal transplantation

Pharmacology

  • Selectively inhibits HMG-CoA reductase
  • Lowers plasma cholesterol and lipoprotein levels
  • Increases hepatic LDL receptors for enhanced uptake and catabolism of LDL

Absorption

Rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to 2 hours.

Distribution

  • Mean volume of distribution is approximately 381 liters
  • 98% bound to plasma proteins

Metabolism

  • Extensively metabolized to ortho- and parahydroxylated derivatives
  • Metabolized by cytochrome P450 3A4

Excretion

  • Eliminated primarily in bile
  • Mean plasma elimination half-life is approximately 14 hours

Interaction

  • Risk of myopathy with concurrent administration of cyclosporine, fibric acid derivatives, niacin, erythromycin, azole antifungals
  • Interactions with antacids, colestipol, digoxin, erythromycin, oral contraceptives, warfarin

Contraindications

  • Hypersensitivity to any component
  • Active liver disease or unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia

Pregnancy lactation

  • Contraindicated during pregnancy
  • Not known if excreted in human milk; contraindicated during breastfeeding

Precautions warnings

  • Liver function tests should be performed before initiation of treatment and periodically thereafter
  • Use with caution in patients who consume substantial alcohol
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

Special populations

  • Plasma concentrations are higher in elderly subjects
  • No significant difference in LDL-C reduction between men and women
  • Renal disease has no influence on plasma concentrations or LDL-C reduction
  • Hemodialysis is not expected to significantly enhance clearance
  • Markedly increased plasma concentrations in patients with chronic alcoholic liver disease

Overdose effects

Specific treatment not available; symptomatic and supportive measures instituted

Storage conditions

Keep in a dry place away from light and heat; Keep out of the reach of children

Chemical structure

  • Molecular Formula: C33H35FN2O5

Common questions

  • What is Atostin 10 mg Tablet?
  • How should I take Atostin 10 mg Tablet?
  • What are the uses of Atostin 10 mg Tablet?
  • What are the Side Effects of Atostin 10 mg Tablet?
  • What are the instructions for storage and disposal Atostin 10 mg Tablet?
  • Is Atostin 10 mg Tablet used for lowering cholesterol?
  • Will taking Atostin 10 mg Tablet increase my risk of diabetes?
  • For how long do I need to take Atostin 10 mg Tablet? Is it safe for long-term use?
  • Does Atostin 10 mg Tablet cause weight loss?
  • Can I stop taking Atostin 10 mg Tablet?
  • Does Atostin 10 mg Tablet cause memory loss?
  • Does Atostin 10 mg Tablet make you tired?
  • Can Atostin 10 mg Tablet be prescribed to children?
  • Is Atostin 10 mg Tablet a blood thinner?
  • Quick Tips

Related Brands