Clonac TR 100 mg (Capsule (Timed Release))

Unit Price: ৳ 3.01 (5 x 10: ৳ 150.50)
Strip Price: ৳ 30.10

Medicine Details

Category Details
Generic Diclofenac sodium
Company Somatec pharmaceuticals ltd

Indications

  • Rheumatology
  • Inflammatory and degenerative forms of rheumatism
  • Chronic involutive polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Spondylarthroses
  • Acute gout
  • Peri-articular rheumatic disorders
  • Sprain
  • Bruises
  • Dislocations
  • Fractures
  • Soft tissue injuries
  • Surgical interventions
  • Primary dysmenorrhoea
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication for the prevention of pain
  • Inflammation
  • Swelling
  • Post-operative pain
  • Post-traumatic pain
  • Prevention of pain and treatment of inflammation and swelling for patients operated in the urogenital tract
  • Renal colic
  • Biliary colic

Pharmacology

  • Potent non-steroidal anti-inflammatory drug (NSAID)
  • Pronounced anti-rheumatic properties
  • Anti-inflammatory properties
  • Analgesic properties
  • Antipyretic properties
  • Uricosuric effect
  • Inhibition of prostaglandin biosynthesis
  • Rapid and complete absorption from the gastrointestinal tract
  • Metabolism in the liver
  • First pass metabolism

Dosage & Administration

  • Diclofenac FC Tablet: 75-150 mg daily in 2 to 3 divided doses for adults
  • Diclofenac SR Tablet: 1 tablet daily for adults, 1-3 mg/kg body weight daily in divided doses for children
  • Diclofenac Dispersible Tablet: 2-3 tablets daily for adults, 1-3 mg/kg body weight for children
  • Diclofenac TR Capsule: One capsule daily
  • Diclofenac Suppository: 50 mg suppository 2-3 times daily for adults
  • Diclofenac injection: 1 ampoule daily for adults, up to 2 ampoules daily in serious cases
  • Diclofenac Gel: 2-4 g of gel applied 3-4 times daily for external use only

Interaction

  • Increase in plasma concentrations of lithium and digoxin
  • Increased risk of haemorrhage with combined use of diclofenac and anticoagulant therapy
  • No influence on clinical effect of oral antidiabetic agents
  • Cases of nephrotoxicity with concomitant use of cyclosporin and diclofenac
  • Serious toxicity when methotrexate and NSAIDs are given within 24 hours
  • Convulsions due to interaction between quinolones and NSAIDs
  • Increase in frequency of unwanted effects with co-administration of diclofenac with other systemic NSAIDs and steroids

Contraindications

  • Hypersensitivity to any ingredient of the product
  • Peptic ulcer
  • Hypersensitivity to Diclofenac or other non-steroid anti-inflammatory agents
  • Contra-indicated in asthmatic patients with attacks precipitated by acetylsalicylic acid or other drugs with prostaglandin synthetase inhibitor
  • Not to be used under occlusive airtight dressings

Side Effects

  • Mild, rare, and transient adverse effects
  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions such as rash and eczema
  • Local irritation and reddening of the skin
  • Skin rash

Pregnancy & Lactation

  • Use only for compelling reasons during pregnancy
  • Lowest effective dose to be used
  • Not recommended during the first trimester of pregnancy
  • Not recommended during lactation
  • Insignificant quantity detected in breast milk with no expected undesirable effects on the infant

Precautions & Warnings

  • Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
  • Close observation in advanced age patients
  • Avoid contact with eyes or mucus membranes
  • Proper hand washing after application
  • Not to be taken by mouth

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Cool and dry place
  • Protected from light
  • Store below 30°C
  • Keep out of the reach of children

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