Clonac TR 100 mg (Capsule (Timed Release))
Unit Price: ৳ 3.01 (5 x 10: ৳ 150.50)
Strip Price: ৳ 30.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Somatec pharmaceuticals ltd |
Indications
- Rheumatology
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication for the prevention of pain
- Inflammation
- Swelling
- Post-operative pain
- Post-traumatic pain
- Prevention of pain and treatment of inflammation and swelling for patients operated in the urogenital tract
- Renal colic
- Biliary colic
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Pronounced anti-rheumatic properties
- Anti-inflammatory properties
- Analgesic properties
- Antipyretic properties
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Rapid and complete absorption from the gastrointestinal tract
- Metabolism in the liver
- First pass metabolism
Dosage & Administration
- Diclofenac FC Tablet: 75-150 mg daily in 2 to 3 divided doses for adults
- Diclofenac SR Tablet: 1 tablet daily for adults, 1-3 mg/kg body weight daily in divided doses for children
- Diclofenac Dispersible Tablet: 2-3 tablets daily for adults, 1-3 mg/kg body weight for children
- Diclofenac TR Capsule: One capsule daily
- Diclofenac Suppository: 50 mg suppository 2-3 times daily for adults
- Diclofenac injection: 1 ampoule daily for adults, up to 2 ampoules daily in serious cases
- Diclofenac Gel: 2-4 g of gel applied 3-4 times daily for external use only
Interaction
- Increase in plasma concentrations of lithium and digoxin
- Increased risk of haemorrhage with combined use of diclofenac and anticoagulant therapy
- No influence on clinical effect of oral antidiabetic agents
- Cases of nephrotoxicity with concomitant use of cyclosporin and diclofenac
- Serious toxicity when methotrexate and NSAIDs are given within 24 hours
- Convulsions due to interaction between quinolones and NSAIDs
- Increase in frequency of unwanted effects with co-administration of diclofenac with other systemic NSAIDs and steroids
Contraindications
- Hypersensitivity to any ingredient of the product
- Peptic ulcer
- Hypersensitivity to Diclofenac or other non-steroid anti-inflammatory agents
- Contra-indicated in asthmatic patients with attacks precipitated by acetylsalicylic acid or other drugs with prostaglandin synthetase inhibitor
- Not to be used under occlusive airtight dressings
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation and reddening of the skin
- Skin rash
Pregnancy & Lactation
- Use only for compelling reasons during pregnancy
- Lowest effective dose to be used
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation
- Insignificant quantity detected in breast milk with no expected undesirable effects on the infant
Precautions & Warnings
- Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
- Close observation in advanced age patients
- Avoid contact with eyes or mucus membranes
- Proper hand washing after application
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children