Gabamet 50 mg (Capsule)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Pregabalin
Company Somatec pharmaceuticals ltd
Also available as
Gabamet 25 mg capsule Gabamet 75 mg capsule

Title

Gabamet 50 mg Capsule

Categories

  • Neuropathic Pain Medication
  • Anticonvulsant
  • Fibromyalgia Treatment
  • Adjunctive Therapy
  • Neurological Medication

Description

Gabamet 50 mg Capsule is used to treat neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, fibromyalgia, and as an adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older. It is also indicated for the management of neuropathic pain associated with spinal cord injury.

Indication

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues
  • Anti-nociceptive and antiseizure effects

Dosage

  • NeuropathicPainAssociatedWithDiabeticPeripheralNeuropathy:
    • Initial: 50 mg three times a day
    • Maximum: 100 mg three times a day
  • PostherpeticNeuralgia:
    • Initial: 75 mg two times a day or 50 mg three times a day
    • Maximum: 300 mg/day
  • Fibromyalgia:
    • Initial: 75 mg two times a day
    • Maximum: 450 mg/day
  • NeuropathicPainAssociatedWithSpinalCordInjury:
    • Recommended dose range: 150 to 600 mg/day
  • AdditionalDosageInfo: Doses may be adjusted based on individual patient response and tolerability.

Administration

  • RouteOfAdministration: Oral
  • Suggestion: Swallow whole with or without food; Pregabalin CR tablet should be administered after an evening meal

Interaction

  • Medication: Unlikely to be involved in significant pharmacokinetic drug interactions
  • FoodAndOthers: Not applicable

Contraindications

  • Known hypersensitivity to Pregabalin or any of its components

SideEffects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Difficulty with concentration/attention
  • Increased weight and appetite in pediatric patients

PregnancyAndLactation

  • No adequate and well-controlled studies in pregnant women
  • Potential risk to fetus
  • Small amounts detected in the milk of lactating women
  • Breastfeeding not recommended during treatment due to potential tumorigenicity

PrecautionsAndWarnings

  • Occurrence of angioedema and hypersensitivity reactions
  • Increased risk of suicidal thoughts or behavior
  • Potential for respiratory depression
  • Potential to cause dizziness and somnolence
  • Risk of increased seizure frequency if rapidly discontinued
  • Potential to cause peripheral edema

UseInSpecialPopulations

  • Safety and effectiveness not established in pediatric patients
  • Safety and effectiveness not established in pediatric patients below the age of 1 month

OverdoseEffects

  • Signs and symptoms: reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, heart block
  • No specific antidote, supportive care indicated

TherapeuticClass

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

StorageConditions

Keep in a cool & dry place (below 30°C), protected from light & moisture. Keep out of the reach of children.

ChemicalStructure

  • MolecularFormula: C8H17NO2
  • ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg

CommonQuestions

  • WhatIsGabamet50mgCapsule: An anticonvulsant used for the treatment of neuropathic pain, shingles, seizures, and fibromyalgia
  • ImprovementDuration: Take until improvement is seen
  • FrequencyOfUse: As prescribed by the doctor
  • UsageWithOrWithoutFood: After food as prescribed
  • StorageAndDisposal: Keep in a cool, dry place and in its original packaging; Keep out of reach of children and pets
  • UniformityOfAction: Works differently for different diseases
  • DurationOfUse: Depends on the condition; Seek doctor's advice before discontinuing
  • ContinuingUseEvenIfFeelingFine: Continue use as advised by the doctor
  • UsageWithDiazepam: Yes, can be used together
  • WeightGainPossibility: May cause weight gain due to increased hunger; Consult a dietician if concerned
  • QuickTips:
    • Take as per doctor's prescription
    • May cause sleepiness, avoid activities requiring concentration
    • May cause vision changes, inform your doctor
    • Do not stop suddenly without consulting your doctor

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