Lodical 5 mg (Tablet)

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Indications

  • Essential hypertension
  • Angina pectoris
  • Vasospastic angina

Pharmacology

  • Calcium-channel blocker
  • Vasodilation
  • Blood pressure reduction
  • Increased coronary blood flow

Dosage & Administration

  • Usual dose 5mg once daily
  • Maximum dose 10mg once daily
  • May be taken without regard to meals

Interaction

  • Potentially hazardous interactions with p-blockers
  • No interaction with Digoxin
  • No interaction with Cimetidine
  • No significant alteration of effect of Warfarin
  • Food does not alter absorption rate

Contraindications

  • Hypersensitivity to dihydropyridine derivatives
  • Pregnancy

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Gastrointestinal disturbances
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Mental depression
  • Ischaemic chest pain
  • Excessive fall in blood pressure
  • Rashes
  • Fever
  • Abnormalities in liver function

Pregnancy & Lactation

  • Pregnancy Category C
  • Potential risk to the fetus
  • Recommendation to discontinue nursing while administered

Precautions & Warnings

  • Hepatic impairment caution
  • Pregnancy caution
  • Breastfeeding caution

Use in Special Populations

  • Starting dose for children with hypertension 2.5mg once daily
  • No data on blood pressure effect in children under 6 years of age
  • Elderly equally well tolerated
  • Normal dosage recommended for renal impairment
  • Cautious dosage in hepatic impairment

Overdose Effects

  • Excessive peripheral vasodilatation
  • Possibly reflex tachycardia
  • Marked and prolonged systemic hypotension
  • Clinical management for hypotension
  • Vasoconstrictor usage
  • Possible use of intravenous calcium gluconate
  • Gastric lavage may be worthwhile

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Keep out of reach of children
  • Store in cool & dry place
  • Protected from light

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