Lodical Plus 5 mg+50 mg (Tablet)
Unit Price: ৳ 6.50 (5 x 10: ৳ 325.00)
Strip Price: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atenolol |
| Company | Somatec pharmaceuticals ltd |
Indications
- Essential hypertension
- Angina pectoris & hypertension
- Post Ml patients
- Refractory angina pectoris
Pharmacology
- Fixed-dose combination of Amlodipine and Atenolol
- Dihydropyridine calcium antagonist
- Peripheral vasodilator
- Cardioselective beta-blocker
- Reduction in blood pressure
- Reduction in myocardial oxygen demand
Dosage & Administration
- Recommended dosage: Amlodipine and Atenolol 5/25 mg tablet once daily
- Dosage may be increased to 5/25 mg twice daily
- Dosage should be individualized
Interaction
- Disopyramide: Atenolol reduces clearance by 20%
- Disopyramide may produce additive negative inotropic effects
- Ampicillin: May reduce Atenolol levels
- Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Fatigue
- Headache
- Edema
- Nausea
- Drowsiness
- Anxiety
- Depression
Pregnancy & Lactation
- Use during pregnancy only if expected benefit outweighs potential fetal risk
- Not recommended for nursing mothers
Precautions & Warnings
- Caution in patients with airway obstruction
- Can be used in patients with renal impairment with caution
- Caution in the use of the combination in patients with severe liver damage
- Patients should be warned against stopping the drug suddenly
Overdose Effects
- Hypotension
- Congestive cardiac failure
- Unabsorbed drugs may be removed by gastric lavage or activated charcoal
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C
- Away from light & moisture
- Keep out of the reach of children