Lindex 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 85.00

Medicine Details

Category Details
Generic Cephradine
Company Rangs pharmaceuticals ltd
Also available asLindex 250 mg capsuleLindex 500 mg capsuleLindex 125 mg suspensionLindex ds 250 mg suspensionLindex 125 mg pediatric dropLindex 500 mg injection

Indications

  • Treatment of upper respiratory tract infections
  • Treatment of lower respiratory tract infections
  • Treatment of urinary tract infections
  • Treatment of skin and soft tissue infections
  • Susceptible microorganisms (gram-positive)
  • Susceptible microorganisms (gram-negative)

Pharmacology

  • Broad spectrum bactericidal antibiotic
  • Active against gram-positive and gram-negative microorganisms
  • Inhibition of cross-linking process in cell wall of bacteria
  • Formation of cell wall pores leading to bacterial cell lysis

Dosage & Administration

  • Recommended dosage for adults with urinary tract infections
  • Recommended dosage for adults with respiratory tract infections
  • Recommended dosage for adults with skin and soft tissue infections
  • Total daily dose for children with otitis media
  • Maximum daily dosage for children

Interaction

  • Increased risk of kidney damage with nephrotoxic drugs
  • Enhanced renal toxicity with diuretics and probenecid

Contraindications

  • Hypersensitivity to cephalosporins

Side Effects

  • Gastrointestinal disturbances
  • Hypersensitivity phenomena
  • Occasional skin reactions
  • Rare side effects e.g. glossitis, dizziness, nausea, vomiting
  • Blood and lymphatic system disorders
  • Immune system disorders
  • Psychiatric disorders
  • Nervous system disorders
  • Hepatobiliary disorders
  • Renal and urinary disorders
  • Elevation of certain blood and serum parameters

Pregnancy & Lactation

  • Absence of teratogenicity in animal studies
  • Excretion of medication in breast milk
  • Caution in lactating mothers

Precautions & Warnings

  • Potential for superinfection with prolonged use
  • Cross-sensitivity with penicillins
  • Potential for false positive urine glucose result
  • Dosage adjustment in renal impairment
  • Contains lactose, caution in patients with specific intolerances

Use in Special Populations

  • Recommended doses for patients with renal impairment
  • Additional information for all patients
  • Limitation on pediatric dosages
  • Requirement for bacteriological and clinical monitoring

Overdose Effects

  • Non-specific symptoms (nausea, vomiting, diarrhoea)
  • Supportive treatment
  • Possible need for gastric lavage

Therapeutic Class

  • First generation cephalosporins

Storage Conditions

  • Shelf life of reconstituted suspension (room temperature and refrigerated)
  • Shelf life of injection solutions (room temperature and refrigerated)
  • Variation in color of reconstituted solutions
  • Dispensation only on prescription of a registered physician

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