Ngcef DS 200 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 300.00

Medicine Details

Category Details
Generic Cefixime trihydrate
Company Rangs pharmaceuticals ltd
Also available as
Ngcef 200 mg capsule Ngcef 100 mg suspension Ngcef 400 mg capsule

Title and Categories

  • Ngcef DS 200 mg/5 ml Suspension
  • Third-generation Cephalosporins
  • Antibiotic
  • Orally Active Cephalosporin Antibiotic

Gram-positive Organism

Streptococcus pneumonia

Gram-negative Organism

Escherichia coli

Generic Name

Cefixime

Pharmacological Class

Semisynthetic Cephalosporin Antibiotic

Bactericidal Activity

Marked In-vitro Bactericidal Activity against a Wide Variety of Bacteria

Plasma Concentrations

Easily Achievable Plasma Concentrations

Mechanism of Action

Interferes in the Synthesis of Bacterial Cell Wall

Stable in the Presence of Beta-lactamase Enzyme

1

Absorption

About 40% to 50% with or without food

Recommended Dosage for Adults

200-400 mg daily

Dosage for Children (8 mg/kg/day)

As a single dose or in two divided doses

Dosage for Typhoid in Children

5 mg/kg body weight twice daily for 10-14 days

Dosage in Renal Impairment

May be administered with dosage adjustment

Interaction with Anticoagulant Therapy

May cause increases in prothrombin times

Contraindications

  • Hypersensitivity to Cephalosporin Antibiotics

Side Effects

  • Gastrointestinal Disturbances
  • Diarrhea
  • Nausea
  • Abdominal Pain
  • Dyspepsia
  • Vomiting
  • Flatulence
  • Headache
  • Dizziness
  • Allergies
  • Thrombocytopenia
  • Leukopenia
  • Eosinophilia
  • Change in Liver and Renal Function Tests
  • Genital Pruritis
  • Vaginitis

Pregnancy & Lactation

  • Pregnancy: Use during pregnancy only if clearly needed
  • Lactation: Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Caution in Patients with Hypersensitivity to Other Drugs
  • Caution in Penicillin-Sensitive Patients
  • Caution in Patients with Markedly Impaired Renal Function
  • Alters Normal Flora of the Colon
  • Caution in Pregnancy and Lactation

Overdose Effects

Gastric Lavage may be indicated; no specific antidote exists

Storage Conditions

Keep below 30°C temperature, protected from light & moisture

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-217-cefixime-trihydrate-chemical-structure-3Mg9h2a2PuSZaJk4Uj0Z.svg

Commonly Asked Questions

  • Ngcef DS 200 mg/5 ml Syrup:
    • Description
    • Uses
    • Side Effects
    • Storage and Disposal Instructions
    • Use for Treating Cold and Flu
    • Special Dietary Instructions
    • Usability for Infants
    • Pregnancy Variant Inquiry
    • Interaction with Contraception
    • Interaction with Acetaminophen
    • Time Taken to Work
    • What if Not Getting Better
    • Quick Tips

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