Pregaran 25 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Rangs pharmaceuticals ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), binds with high affinity to the alpha2-delta site in central nervous system tissues
Dosage
Maximum recommended dose of 100 mg three times a day for neuropathic pain associated with diabetic peripheral neuropathy, 75 to 150 mg two times a day or 50 to 100 mg three times a day for postherpetic neuralgia, 300 to 450 mg/day for fibromyalgia, 150 to 600 mg/day for neuropathic pain associated with spinal cord injury
Administration
Oral route, can be taken with or without food, Pregabalin CR tablet should be administered after an evening meal, swallowed whole and should not be split, crushed or chewed
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
- Not applicable for food and others
Contraindications
- Patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Thinking abnormal (primarily difficulty with concentration/attention)
- Increased weight and increased appetite in pediatric patients
Pregnancy & Lactation
No adequate and well-controlled studies with pregabalin in pregnant women, small amounts detected in the milk of lactating women, breastfeeding not recommended
Precautions & Warnings
- Angioedema
- Hypersensitivity reactions
- Increase in the risk of suicidal thoughts or behavior
- Respiratory depression
- May cause dizziness and somnolence
- Increased seizure frequency or other adverse reactions if rapidly discontinued
- May cause peripheral edema
Use in Special Populations
Safety and effectiveness not established in pediatric patients for various conditions
Overdose Effects
Reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, heart block
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture, keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions about Pregaran 25 mg Capsule
- What is Pregaran 25 mg Capsule?: Anticonvulsant and first-line treatment for neuropathic pain, shingles, seizures, and fibromyalgia
- How long do I need to use Pregaran 25 mg Capsule before I see improvement in my condition?: Till the time improvement is observed
- At what frequency do I need to use Pregaran 25 mg Capsule?: As prescribed by the doctor
- Should I use Pregaran 25 mg Capsule empty stomach, before food or after food?: After food as prescribed
- What are the instructions for the storage and disposal of Pregaran 25 mg Capsule?: Keep in a cool dry place, in its original packaging, and away from children and pets
- Does Pregaran 25 mg Capsule work in the same way for each disease?: No, works differently for different diseases
- How long do I need to take Pregaran 25 mg Capsule?: Depends on the condition, consult the doctor
- Is it necessary to continue taking Pregaran 25 mg Capsule even if I feel fine?: Yes, do not stop without consulting the doctor
- Can I take Diazepam and Pregaran 25 mg Capsule together?: Yes, they can be used together
- Can the use of Pregaran 25 mg Capsule cause weight gain?: May cause weight gain due to increased hunger, consult a dietician