Vesodil 25 mg (Tablet)
Unit Price: ৳ 8.03 (3 x 10: ৳ 240.90)
Strip Price: ৳ 80.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Carvedilol |
| Company | Rangs pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of mild, moderate or severe heart failure
- Reduction of disease progression
- Conjunction with digitalis, diuretics, and ACE inhibitor
Pharmacology
- Non-selective antagonism of β-adrenergic receptors
- Antiproliferative properties
- Scavenger of reactive free oxidant radicals
Dosage & Administration
- Initial dose of 12.5 mg once daily for hypertension
- Recommended dose of 25 mg twice daily for angina pectoris
- Initial dose of 3.125 mg twice daily for heart failure
Interaction
- Increased levels of digoxin when taken together with Vesodil
- 60% decrease in Cmax and AUC when pretreated with rifampin
- No alteration of in vitro plasma protein binding of warfarin by Vesodil
Contraindications
- Decompensated heart failure requiring intravenous inotropic therapy
- Bronchial asthma or related bronchospastic conditions
- Second or third-degree AV block
Side Effects
- Postural hypotension
- Dizziness
- Fatigue
- Peripheral oedema
- Dry mouth
- Eye irritation
- Impotence
- Exacerbation of intermittent claudication
Pregnancy & Lactation
- Not recommended during breast-feeding
- Not recommended during pregnancy
- Excreted in breast milk
Precautions & Warnings
- Take caution in hepatic impairment
- Monitor clinical status for 2-3 hours after initiation
Therapeutic Class
- Alpha adrenoceptor blocking drugs
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children