Clopidol 75 mg (Tablet)
Unit Price: ৳ 10.03 (3 x 10: ৳ 300.90)
Strip Price: ৳ 100.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Clopidogrel bisulphate |
| Company | Alco pharma ltd |
Indications
- Reduction of myocardial infarction in ACS patients
- Reduction of stroke in ACS patients
- Reduction of myocardial infarction in Recent MI patients
- Reduction of stroke in Recent Stroke patients
- Reduction of MI and stroke in Peripheral Arterial Disease patients
- Reduction of MI and stroke in STEMI patients
- Reduction of MI and stroke in NSTEMI patients
Pharmacology
- Prodrug
- Inhibition of platelet activation
- Irreversible binding to P2Y12 receptors
- Dose-dependent inhibition of platelet aggregation
Dosage & Administration
- 300 mg oral loading dose for ACS
- 75 mg once daily for Recent MI, Recent Stroke, or Peripheral Arterial Disease
- Oral administration with or without food
Interaction
- Increased bleeding risk with NSAIDs, warfarin, SSRIs, SNRIs
- Avoid concomitant use with CYP2C19 inhibitors
- Increased plasma concentrations of Repaglinide with concomitant use
Contraindications
- Hypersensitivity to the drug
- Active pathological bleeding
Side Effects
- Common: Bleeding, Diarrhoea, gastrointestinal discomfort, Skin reactions
- Rare: Acquired haemophilia, anaemia, angioedema, arthralgia
Pregnancy & Lactation
- Use during pregnancy only if clearly needed
- Uncertain excretion in human breast milk
Precautions & Warnings
- Impaired metabolism with CYP2C19 poor metabolizer or inhibitors
- Risk of bleeding increase due to lifetime platelet inhibition
- Discontinuation increases risk of cardiovascular events
- Reported cases of Thrombotic Thrombocytopenic Purpura
- Reported cases of hypersensitivity reactions
Use in Special Populations
- Safety and effectiveness not established in pediatric populations
- No dosage adjustment necessary in elderly patients
Overdose Effects
- May lead to bleeding complications
- Platelet transfusion may restore clotting ability
Therapeutic Class
- Anti-platelet drugs
Storage Conditions
- Keep below 30°C temperature
- Keep in a dry place
- Protected from light
- Do not freeze
- Keep out of the reach of children