Olmetic 20 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 14: ৳ 378.00)
Strip Price: ৳ 126.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Olmesartan medoxomil |
| Company | Drug international ltd |
Indications
- Treatment of hypertension
- May be used alone or in combination with other antihypertensive agents
Pharmacology
- Blocks vasoconstrictor effects of angiotensin II
- Selectively blocks the binding of angiotensin II to the AT 1 receptor in vascular smooth muscle
- Does not inhibit ACE (kininase II), does not affect the response to bradykinin
- Inhibits the negative regulatory feedback of angiotensin II on renin secretion
Dosage & Administration
- Usual recommended starting dose of 20 mg once daily
- Dose may be increased to 40 mg for patients requiring further reduction in blood pressure
- Twice-daily dosing offers no advantage over once daily dosing
- No initial dosage adjustment recommended for elderly patients or patients with moderate to marked renal impairment or hepatic dysfunction
- May be administered with or without food
Interaction
- No significant drug interactions reported with digoxin or warfarin
- Bioavailability not significantly altered by the co-administration of antacids
- Not metabolized by the cytochrome P450 system
- Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) including selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors) may result in deterioration of renal function
- Monitor renal function periodically in patients receiving Olmetic and NSAID therapy
Contraindications
- Hypersensitivity to any component of this product
Side Effects
- Well tolerated with incidence of adverse reactions similar to placebo
- Dizziness may occur
- Other adverse reactions occurred in placebo-controlled clinical trials
Pregnancy & Lactation
- Discontinue if pregnancy is detected
- Drugs that act directly on the renin-angiotensin system can cause injury to the developing fetus
- Potential for adverse effects on the nursing infant
Precautions & Warnings
- Changes in renal function may be anticipated in susceptible individuals treated with Olmetic
- Treatment has been associated with oliguria, progressive azotemia, and acute renal failure in certain patients
Overdose Effects
- Hypotension and tachycardia are the most likely effects of overdose
- Bradycardia may occur with parasympathetic (vagal) stimulation
- Clinically significant hypotension requires active support of the cardiovascular system
Therapeutic Class
- Angiotensin-II receptor blocker
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C29H30N6O6
Common Questions about Olmetic 20 mg Tablet
- Used to treat high blood pressure
- Average time taken to reach peak effect is around 1 day to 1 week
- Generally used once or twice a day
- Oral consumption advised
- Storage at room temperature, away from heat and direct light