Emiset 4 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 45.00

Medicine Details

Category Details
Generic Ondansetron
Company Alco pharma ltd
Also available as
Emiset 8 mg tablet

Indications

  • Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Formulation

Oral soluble film

Active Ingredient

Ondansetron

Molecular Weight

293.3

Target Receptor

5-HT3 receptor

Dosage Forms

  • Tablet
  • Orodispersible tablet
  • Injection
  • Oral Solution

Dosage Instructions

  • Adults, Pediatric patients (6 months to 18 years)
  • Adults
  • Pediatrics (>40 kg)
  • Pediatrics (40 kg)
  • Adults/Geriatric/Child of 12 years or over
  • Pediatric (4-11 years)
  • The recommended oral dosage for Radiotherapy induced Nausea and Vomiting
  • Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy
  • Prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy
  • Prevention of nausea and vomiting associated with radiotherapy
  • Postoperative nausea and vomiting
  • Adult oral dose for Oral Soluble Film

Administration Instructions

  • Tear the pouch carefully along with the edge tear mark
  • Put the Ondansetron film on top of your tongue and allow it to dissolve
  • Do not chew or swallow the film whole
  • Swallow after the film dissolves
  • Wash your hands after taking the film

Drug Interaction

Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes, inducers or inhibitors may change the clearance and hence the half-life of Ondansetron.

Contraindications

  • Hypersensitivity to the drug or any of its components
  • Concomitant use of apomorphine

Side Effects

  • Headache
  • Constipation
  • Diarrhea
  • Rash
  • Sensation of flushing or warmth
  • Hiccups
  • Liver enzyme abnormalities
  • Anaphylaxis
  • Brochospasm
  • Tachycardia
  • Angina
  • Hypokalemia
  • Shortness of breath
  • Extrapyramidal reactions
  • Oculogyric crisis
  • Pregnancy & Lactation
  • Carcinogenic effects were not seen in 2-year studies in rats and mice with oral Ondansetron doses up to 10 and 30 mg/kg per day
  • Ondansetron was not mutagenic in standard tests for mutagenicity

Precautions & Warnings

  • Hypersensitivity reactions
  • Not a drug that stimulates gastric or intestinal peristalsis
  • Should not be used instead of nasogastric suction
  • Use in patients following abdominal surgery may mask a progressive ileus and/or gastric distension

Drug Class

Anti-emetic

Storage Conditions

Store at temperature not exceeding 30°C in a dry place, Protect from light and moisture

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