Esopra 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 7.02 (3 x 14: ৳ 295.00)
Strip Price: ৳ 98.33

Medicine Details

Category Details
Generic Esomeprazole
Company Alco pharma ltd
Also available as
Esopra 20 mg tablet Esopra 20 mg capsule Esopra 40 mg capsule

Indications

  • Relief from chronic heartburn symptoms and other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Treatment of duodenal & gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase in the gastric parietal cell
  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Metabolized in the liver by cytochrome P450 (CYP) enzyme system

Dosage

  • Oral dosage form for different conditions
  • IV injection or infusion for specific cases

Administration

  • Swallowing the tablet or capsule whole, taken before a meal
  • Preparation and administration of oral suspension
  • Preparation of IV injection solution

Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • Potential interference with drug absorption due to gastric pH changes
  • No clinically significant interactions with certain drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No studies on excretion in milk
  • Consideration for discontinuing breastfeeding if essential use

Precautions & Warnings

  • Symptomatic response does not exclude gastric malignancy
  • Administration timing and method for patients with difficulty swallowing capsules
  • Use of antacids while taking Esopra

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy in the elderly
  • No dosage adjustment for hepatic insufficiency
  • No expected alteration in pharmacokinetics in patients with renal impairment

Overdose Effects

  • Lethal effects observed in rats at high doses
  • Symptomatic and supportive treatment recommended
  • No specific antidote known

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image URL

Common Questions about Esopra 40 mg Tablet

  • Description of the tablet's function
  • Common uses
  • Side effects
  • Pregnancy and breastfeeding considerations
  • Onset of action
  • Quick tips for usage

Other Attributes

  • Multiple uses of the tablet for different conditions
  • Comparative effectiveness between short-term and long-term use

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