Esopra 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.02 (6 x 10: ৳ 361.20)
Strip Price: ৳ 60.20

Medicine Details

Category Details
Generic Esomeprazole
Company Alco pharma ltd
Also available as
Esopra 20 mg tablet Esopra 40 mg tablet Esopra 40 mg capsule

Title

Esopra 20 mg Capsule

Categories

  • Medication
  • Pharmaceutical
  • Gastrointestinal

Description

A proton pump inhibitor (PPI) used to treat chronic heartburn (GERD), erosive esophagitis, Helicobacter pylori infection, Zollinger-Ellison Syndrome, and other acid-related dyspepsia. Available in oral dosage forms and IV injection, Esopra has specific indications, dosage recommendations, administration guidelines, and potential drug interactions.

Attributes

  • Dosage Forms:
    • Oral capsule
    • Oral suspension
    • IV injection
  • Indications:
    • Relief of chronic heartburn symptoms
    • Healing of erosive esophagitis
    • Maintenance of healing of erosive esophagitis
    • Eradication of Helicobacter pylori infection
    • Treatment for Zollinger-Ellison Syndrome
    • Symptomatic GERD relief
    • Duodenal ulcer and gastric ulcer treatment
  • Mode of Action:
    • Proton pump inhibitor
    • Suppression of gastric acid secretion
    • Specific inhibition of H+/K+-ATPase
    • Single optical isomer of proton pump inhibitor
  • Pharmacokinetics:
    • Absorption through enteric-coated pellets
    • Peak plasma levels at approximately 1.5 hours
    • Metabolism through CYP2C19 and CYP3A4
    • Excretion via urine and faeces
    • Increased bioavailability during triple therapy
  • Interaction:
    • Metabolism by CYP2C19 and CYP3A4
    • Potential interference with CYP2C19 substrates
    • Inhibition of gastric acid secretion affecting drug absorption
  • Contraindications:
    • Known hypersensitivity to the formulation
  • Side Effects:
    • Headache
    • Diarrhea
    • Nausea
    • Flatulence
    • Abdominal pain
    • Constipation
    • Dry mouth
  • Pregnancy & Lactation:
    • No adequate and well-controlled studies in pregnant women
    • No teratogenic effects in animal studies
    • Excretion in milk not studied
    • Discontinuation of breastfeeding if essential
  • Precautions & Warnings:
    • Symptomatic response does not exclude gastric malignancy
    • Guidelines for patients with difficulty swallowing capsules
    • Use of antacids during treatment
  • Special Populations:
    • Pediatric use not established
    • No significant differences observed in geriatric use
    • No dosage adjustment in mild to moderate hepatic insufficiency
    • Expected unchanged pharmacokinetics in renal impairment
  • Overdose Effects:
    • Lethal in rats at high doses
    • No specific antidote known
    • Symptomatic and supportive treatment recommended
  • Storage Conditions:
    • Store at a temperature not exceeding 30°C
    • Protect from light and moisture
    • Keep out of reach of children
  • Chemical Structure:
    • Molecular formula: C17H19N3O3S
    • Chemical structure image available
  • Commonly Asked Questions:
    • Uses of Esopra 20 mg Capsule
    • Side effects and pregnancy/lactation considerations
    • Onset of action and quick tips for usage

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