Esopra 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.03 (5 x 6: ৳ 270.90)
Strip Price: ৳ 54.18

Medicine Details

Category Details
Generic Esomeprazole
Company Alco pharma ltd
Also available as
Esopra 20 mg tablet Esopra 40 mg tablet Esopra 20 mg capsule

Title

  • Esopra 40 mg Capsule

Categories

  • Medicine
  • Healthcare
  • Gastroenterology

Description

  • Esopra 40 mg Capsule is a proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), ulcers, and conditions involving excess stomach acid.

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Relief from Acid related Dyspepsia
  • Treatment of Duodenal & Gastric ulcers

Pharmacology

  • Esomeprazole suppresses gastric acid secretion
  • Peak plasma levels occur at approximately 1.5 hours after oral administration
  • Metabolized in the liver by the cytochrome P450 (CYP) enzyme system
  • Plasma elimination half-life is approximately 1–1.5 hours

Dosage

  • 20 mg or 40 mg Once Daily for Healing of Erosive Esophagitis
  • 20 mg Once Daily for Maintenance of Healing of Erosive Esophagitis
  • 20 mg Once Daily for Symptomatic GERD
  • Triple Therapy for Helicobacter Pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for Acid-related Dyspepsia
  • 20 mg once daily for Duodenal ulcer; 20-40 mg once daily for Gastric ulcer
  • Dosage also available for IV Injection or IV infusion for certain conditions

Administration

  • Tablets or capsules should be swallowed whole and taken one hour before a meal
  • Oral suspension should be mixed with water and taken immediately
  • IV solution for injection should be administered intravenously over a period of at least 3 minutes

Interaction

  • Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
  • May interfere with the absorption of drugs where gastric pH is important for bioavailability

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Capsules can be taken with applesauce for patients who have difficulty swallowing

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed between elderly and younger individuals

Overdose Effects

  • High doses have been lethal in animals
  • No specific antidote known
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Store at a temperature not exceeding 30°C in a dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure available as an image

Commonly Asked Questions

  • Information about uses, side effects, pregnancy, and tips for taking the medicine

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