Esopra 40 mg (Capsule (Enteric Coated))
Unit Price: ৳ 9.03 (5 x 6: ৳ 270.90)
Strip Price: ৳ 54.18
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Alco pharma ltd |
| Also available as |
Title
- Esopra 40 mg Capsule
Categories
- Medicine
- Healthcare
- Gastroenterology
Description
- Esopra 40 mg Capsule is a proton pump inhibitor (PPI) used to treat gastroesophageal reflux disease (GERD), ulcers, and conditions involving excess stomach acid.
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Relief from Acid related Dyspepsia
- Treatment of Duodenal & Gastric ulcers
Pharmacology
- Esomeprazole suppresses gastric acid secretion
- Peak plasma levels occur at approximately 1.5 hours after oral administration
- Metabolized in the liver by the cytochrome P450 (CYP) enzyme system
- Plasma elimination half-life is approximately 1–1.5 hours
Dosage
- 20 mg or 40 mg Once Daily for Healing of Erosive Esophagitis
- 20 mg Once Daily for Maintenance of Healing of Erosive Esophagitis
- 20 mg Once Daily for Symptomatic GERD
- Triple Therapy for Helicobacter Pylori eradication
- 20-80 mg once daily for Zollinger-Ellison Syndrome
- 20-40 mg once daily for Acid-related Dyspepsia
- 20 mg once daily for Duodenal ulcer; 20-40 mg once daily for Gastric ulcer
- Dosage also available for IV Injection or IV infusion for certain conditions
Administration
- Tablets or capsules should be swallowed whole and taken one hour before a meal
- Oral suspension should be mixed with water and taken immediately
- IV solution for injection should be administered intravenously over a period of at least 3 minutes
Interaction
- Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
- May interfere with the absorption of drugs where gastric pH is important for bioavailability
Contraindications
- Contraindicated in patients with known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Excretion in milk not studied
- Breastfeeding should be discontinued if essential
Precautions & Warnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Capsules can be taken with applesauce for patients who have difficulty swallowing
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety and efficacy observed between elderly and younger individuals
Overdose Effects
- High doses have been lethal in animals
- No specific antidote known
- Treatment should be symptomatic and supportive
Storage Conditions
- Store at a temperature not exceeding 30°C in a dry place
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure available as an image
Commonly Asked Questions
- Information about uses, side effects, pregnancy, and tips for taking the medicine