Metmin XR 500 mg (Tablet (Extended Release))

Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Alco pharma ltd
Also available as
Metmin 850 mg tablet Metmin 500 mg tablet

Indications

  • Treatment of type 2 diabetes mellitus in adults
  • Diabetic complications reduction in overweight patients
  • Monotherapy or combination therapy for adults and children

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers basal and postprandial plasma glucose
  • Improves insulin sensitivity

Dosage & Administration

  • Individualized dosage based on effectiveness and tolerance
  • Immediate release and extended release tablet options
  • Usual starting dose for adults and children
  • Renal impaired patient precautions

Interaction

  • Interaction with Furosemide and Nifedipine
  • Potential interaction with cationic drugs
  • Effects on Cimetidine pharmacokinetics
  • Drugs causing hyperglycemia and loss of glycemic control

Contraindications

  • Hypersensitivity to active substance or excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Conditions altering renal function or causing tissue hypoxia

Side Effects

  • Blood and lymphatic system disorders
  • Metabolism and nutrition disorders
  • Nervous system disorders
  • Gastrointestinal disorders
  • Hepatobiliary disorders
  • Skin and subcutaneous tissue disorders

Pregnancy & Lactation

  • Risks associated with uncontrolled diabetes during pregnancy
  • Excretion into human breast milk
  • Adverse effects on breastfed newborns/infants

Precautions & Warnings

  • Substantial excretion by the kidney
  • Lowering of vitamin B12 level
  • Increased risk of hypoglycemia with insulin
  • Regular monitoring of renal function
  • Pre-surgery cessation and post-surgery reinstatement
  • Annual estimation of Vitamin B-12 levels
  • Interaction with sulphonylurea and anticoagulants

Use in Special Populations

  • Dosage adjustments for elderly subjects
  • Effect on growth and puberty
  • Caution in prescribing to children aged between 10 and 12 years
  • Renal function assessment and precautions

Overdose Effects

  • Hypoglycemia and lactic acidosis risk
  • Treatment in hospital
  • Hemodialysis for lactate and drug removal

Therapeutic Class

  • Biguanides

Storage Conditions

  • Below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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