Metmin XR 500 mg (Tablet (Extended Release))
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Alco pharma ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus in adults
- Diabetic complications reduction in overweight patients
- Monotherapy or combination therapy for adults and children
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Immediate release and extended release tablet options
- Usual starting dose for adults and children
- Renal impaired patient precautions
Interaction
- Interaction with Furosemide and Nifedipine
- Potential interaction with cationic drugs
- Effects on Cimetidine pharmacokinetics
- Drugs causing hyperglycemia and loss of glycemic control
Contraindications
- Hypersensitivity to active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Conditions altering renal function or causing tissue hypoxia
Side Effects
- Blood and lymphatic system disorders
- Metabolism and nutrition disorders
- Nervous system disorders
- Gastrointestinal disorders
- Hepatobiliary disorders
- Skin and subcutaneous tissue disorders
Pregnancy & Lactation
- Risks associated with uncontrolled diabetes during pregnancy
- Excretion into human breast milk
- Adverse effects on breastfed newborns/infants
Precautions & Warnings
- Substantial excretion by the kidney
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia with insulin
- Regular monitoring of renal function
- Pre-surgery cessation and post-surgery reinstatement
- Annual estimation of Vitamin B-12 levels
- Interaction with sulphonylurea and anticoagulants
Use in Special Populations
- Dosage adjustments for elderly subjects
- Effect on growth and puberty
- Caution in prescribing to children aged between 10 and 12 years
- Renal function assessment and precautions
Overdose Effects
- Hypoglycemia and lactic acidosis risk
- Treatment in hospital
- Hemodialysis for lactate and drug removal
Therapeutic Class
- Biguanides
Storage Conditions
- Below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children