Infecef 1 gm/vial (IM Injection)

1 gm vial: ৳ 190.58

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Alco pharma ltd
Also available as
Infecef 250 mg injection Infecef 500 mg injection Infecef 1 gm injection Infecef 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute bacterial otitis media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibiotic
  • Bactericidal activity
  • Long plasma elimination half-life
  • Stable against beta-lactamases
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Usual adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum adult dose: 4 gm/day
  • Usual pediatric dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Maximum pediatric dose: 2 gm/day
  • Duration of therapy: 4 to 14 days

Administration

  • Preparation of solutions for intramuscular/intravenous injections
  • Recommended injection duration and concentration
  • Patient tolerance test before starting treatment
  • Solution stability at room temperature and 5°C

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis after intravenous administration

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution in lactating mothers

Precautions & Warnings

  • Potential for anaphylactic shock
  • Potential for gallbladder sludge
  • Blood picture should be checked during prolonged treatment

Use in Special Populations

  • Avoid use in premature and newborn neonates (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30°C)
  • Keep away from light and moisture

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