Infecef 2 gm/vial (IV Injection)
2 gm vial: ৳ 320.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Alco pharma ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum antibacterial
- Potent bactericidal activity
- High degree of stability in the presence of beta lactamases
- Long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Highly protein bound (95%)
Dosage
- Adult: 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
- Infants and Children (01 month or older): 50 to 75 mg/kg intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
- Duration of therapy: 4 to 14 days; in complicated infections, longer therapy may be required
Administration
- Intramuscular Injection with Lidocaine HCI 1%
- Intravenous Injection with Water for injection
- Administered over 2-4 minutes
- Freshly reconstituted solution recommended
Interaction
No drug interactions reported
Contraindications
Not to be given to patients with a history of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects including diarrhea, nausea, vomiting
- Cutaneous reactions including rash, pruritus, urticaria
- Hematologic reactions including eosinophilia, thrombocytopenia
- Hepatic reactions including elevations of SGOT or SGPT
- CNS reactions including nervousness, confusion, headache
- Local phlebitis occurs rarely following intravenous administration
Pregnancy & Lactation
Safety in human pregnancy not established, caution during lactation
Precautions & Warnings
- Anaphylactic shock may occur
- Gallbladder sludge may be detected, reversible on discontinuation of therapy
- Blood picture should be checked during prolonged treatment
Use in Special Populations
Not to be given to premature neonates up to 28 days of age
Overdose Effects
No specific antidote. Treatment should be symptomatic
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Store below 30° C, away from light & moisture, Keep out of the reach of children