Infecef 2 gm/vial (IV Injection)

2 gm vial: ৳ 320.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Alco pharma ltd
Also available as
Infecef 250 mg injection Infecef 500 mg injection Infecef 1 gm injection Infecef 1 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibacterial
  • Potent bactericidal activity
  • High degree of stability in the presence of beta lactamases
  • Long plasma elimination half-life of 6 to 9 hours
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Adult: 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
  • Infants and Children (01 month or older): 50 to 75 mg/kg intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
  • Duration of therapy: 4 to 14 days; in complicated infections, longer therapy may be required

Administration

  • Intramuscular Injection with Lidocaine HCI 1%
  • Intravenous Injection with Water for injection
  • Administered over 2-4 minutes
  • Freshly reconstituted solution recommended

Interaction

No drug interactions reported

Contraindications

Not to be given to patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea, vomiting
  • Cutaneous reactions including rash, pruritus, urticaria
  • Hematologic reactions including eosinophilia, thrombocytopenia
  • Hepatic reactions including elevations of SGOT or SGPT
  • CNS reactions including nervousness, confusion, headache
  • Local phlebitis occurs rarely following intravenous administration

Pregnancy & Lactation

Safety in human pregnancy not established, caution during lactation

Precautions & Warnings

  • Anaphylactic shock may occur
  • Gallbladder sludge may be detected, reversible on discontinuation of therapy
  • Blood picture should be checked during prolonged treatment

Use in Special Populations

Not to be given to premature neonates up to 28 days of age

Overdose Effects

No specific antidote. Treatment should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store below 30° C, away from light & moisture, Keep out of the reach of children

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