Staflu DS 250 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 110.75
Medicine Details
| Category | Details |
|---|---|
| Generic | Flucloxacillin sodium |
| Company | Alco pharma ltd |
| Also available as |
Indications
- Skin and soft tissue infections
- Respiratory tract infections
- Osteomyelitis treatment
- Enteritis treatment
- Endocarditis treatment
- Urinary tract infection treatment
- Meningitis treatment
- Septicaemia treatment
- Prophylactic use during major surgical procedures
- Treatment of infected skin conditions
- Treatment of pneumonia
- Treatment of lung abscess
- Treatment of empyema
- Treatment of sinusitis
- Treatment of pharyngitis
- Treatment of tonsillitis
- Propensity for use in cardiothoracic surgeries
- Propensity for use in orthopedic surgeries
Pharmacology
- Active against Gram-positive organisms
- Inhibition of cell wall formation in bacteria
- Resistance to hydrolysis by penicillinase
- Gastric acid stability
- Bactericidal action
- Specifically effective against penicillinase-producing staphylococci
- Mechanism of action involving bacterial cell wall disruption
Dosage
- Oral administration for adults at 250 mg four times daily
- Potential doubling of dosage in severe infections for adults
- Higher dosage (up to 8 gm daily) for osteomyelitis and endocarditis
- Lower dosage for children based on age
- Intramuscular and intravenous administration for adults and elderly
- Dosing frequency for severe infections
- Lower dosage for children based on age
Administration
- Oral doses to be administered 1 hour before meals
Interaction
- Potential for increased blood levels with concurrent use
Contraindications
- Contraindicated for penicillin hypersensitive patients
Side Effects
- Common gastrointestinal side effects such as nausea, vomiting, and diarrhea
- Minor gastrointestinal disturbances
- Rashes and urticaria
- Purpura
- Fever
- Interstitial nephritis
- Hepatitis
- Cholestatic jaundice
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Limited studies in pregnant women
- Excretion in human milk
- Caution advised during lactation
Precautions & Warnings
- Caution in patients with hepatic dysfunction
- Exercise caution in patients with allergic diathesis
Use in Special Populations
- Consideration for reduced dose in severe renal failure
Therapeutic Class
- Penicillinase-resistant penicillins
Reconstitution
- Use in other routes in conjunction with systemic therapy
- Intraarticular injection
- Intrapleural injection
- Inhalation by nebuliser
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children