Active Plus 6 mg+200 mg+50 mg (Tablet)

Unit Price: ৳ 2.50 (30's pack: ৳ 75.00)

Medicine Details

Indications

  • Prevention of coronary heart diseases
  • Prevention of certain types of cancer
  • Aging prevention
  • Defense against free radical damage caused by excessive exercise
  • Defense against free radical damage due to illness
  • Defense against free radical damage caused by certain medications
  • Defense against free radical damage caused by air pollution
  • Defense against free radical damage caused by smoke
  • Defense against free radical damage caused by radiation
  • Defense against free radical damage caused by pesticides

Pharmacology

  • Beta carotene conversion to vitamin A
  • Vitamin A biochemical functions
  • Anti-cancer activity of vitamin A
  • Biochemical functions of vitamin C
  • Cofactor role of vitamin C
  • Vitamin C deficiency leading to scurvy
  • Cofactor role of vitamin C in biological processes
  • Vitamin C role in conversion of proline to hydroxyproline
  • Vitamin C role in conversion of dopamine to noradrenaline
  • Vitamin C role in synthesis of adrenal steroid hormones
  • Vitamin C importance in defense against infection
  • Vitamin E's defense against oxidative stress
  • Vitamin E's role in lipid peroxidation
  • Tocopherol's peroxide radicals mopping up
  • Vitamin E's need for a supply of reduced hydrogen

Dosage & Administration

  • Oral administration
  • Adult dose is 1 tablet daily

Interaction

  • Decreased absorption of β carotene by Cholestyramine
  • Decreased absorption of β carotene by Colestipol
  • Decreased absorption of β carotene by Neomycin
  • Reduced circulating vitamin C levels with oral contraceptives containing Oestrogen
  • Reduced circulating vitamin C levels with Tetracycline
  • Reduced circulating vitamin C levels with Aspirin
  • Enhanced anticoagulant activity of anticoagulant drugs by vitamin E
  • Impairment of intestinal absorption of vitamins A and K by high doses of vitamin E

Contraindications

  • Hypersensitivity to any components

Side Effects

  • Hypercarotenosis due to large carotenoid intake
  • Yellowish coloration of the skin due to large carotenoid intake
  • High concentration of carotenoids in plasma due to large carotenoid intake
  • Gastrointestinal tract upset with larger doses of vitamin C
  • Renal stone formation with larger doses of vitamin C
  • Diarrhoea with doses over 800 mg of vitamin E
  • Abdominal pain or cramps with doses over 800 mg of vitamin E
  • Fatigue with doses over 800 mg of vitamin E
  • Reduced resistance to bacterial infection with doses over 800 mg of vitamin E
  • Transiently raised blood pressure with doses over 800 mg of vitamin E

Pregnancy & Lactation

  • No teratogenic effects of β carotene, vitamin C, and vitamin E in humans
  • Caution advised in prescribing to pregnant women

Precautions & Warnings

  • Caution for heavy smokers and alcoholics when using β carotene
  • Caution for patients with hyperoxaluria when using vitamin C
  • Caution for patients taking anticoagulant drugs when using vitamin E

Therapeutic Class

  • Anti-oxidant Multivitamin preparations

Storage Conditions

  • Store in a dry place below 30˚C

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