Clintrix 1.2%+0.025% (Topical Gel)

15 gm tube: ৳ 150.00

Medicine Details

Category Details
Generic Clindamycin tretinoin
Company The white horse pharmaceuticals ltd

Indications

  • Topical treatment of Acne vulgaris

Pharmacology

  • Combination of lincosamide antibiotic (Clindamycin phosphate) and retinoid (Tretinoin)
  • Clindamycin binds with the 50s ribosomal subunit of susceptible bacteria and prevents elongation of peptide chain
  • Tretinoin decreases the cohesiveness of follicular epithelial cells and increases the turnover of cells
  • Clindamycin inhibits the activity of Propionibacterium acne

Dosage & Administration

  • Application before sleep with gentle face wash
  • Apply sunscreen in the morning after application
  • Avoid washing face more than 2-3 times a day
  • Safety and effectiveness not established in children below 12 years

Interaction

  • Caution with concomitant use of potentially irritating topical products
  • Avoid concomitant use with Erythromycin
  • Careful use with neuromuscular medicine

Contraindications

  • Hypersensitivity to Clindamycin or Tretinoin or any other component of the gel

Side Effects

  • Erythema
  • Scaling
  • Nasopharyngitis
  • Dry skin
  • Cough
  • Sinusitis
  • Diarrhea

Pregnancy & Lactation

  • Not known whether Clindamycin or Tretinoin is excreted in human milk
  • Exercise special caution while applying to a nursing mother

Precautions & Warnings

  • Avoid application to eyes, nose, ear, lips, cuts, burns, and other infections
  • Keep away from sunlight after application

Therapeutic Class

  • Topical antibiotic & retinoid preparations

Storage Conditions

  • Keep below 25°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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