Xyotil 20 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Olmesartan medoxomil |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title
Xyotil 20 mg Tablet
Categories
- Hypertension
- Antihypertensive Agent
- Renin-Angiotensin System Blocker
- Angiotensin II Receptor Blocker
Description
Xyotil 20 mg Tablet is indicated for the treatment of hypertension, and may be used alone or in combination with other antihypertensive agents. It blocks the vasoconstrictor effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT 1 receptor in vascular smooth muscle.
Dosage
Dosage must be individualized. The usual recommended starting dose of Olmesartan is 20 mg once daily when used as monotherapy in patients who are not volume-contracted. For patients requiring further reduction in blood pressure after 2 weeks of therapy, the dose of Olmesartan may be increased to 40 mg. Doses above 40 mg do not appear to have a greater effect.
DosageAdministration
- 20 mg once daily
- 40 mg if further reduction in blood pressure is required
- Twice-daily dosing offers no advantage over the same total dose given once daily
- No initial dosage adjustment is recommended for elderly patients
- For patients with marked renal impairment, lower starting dose is recommended
- May be administered with or without food
- Safety and effectiveness in pediatric patients have not been established
DrugInteraction
- No significant interaction with digoxin or warfarin
- Bioavailability not significantly altered by antacids
- Not metabolized by cytochrome P450 system
- Potential deterioration of renal function when co-administered with NSAIDs, including COX-2 inhibitors
Contraindications
- Hypersensitivity to any component of this product
SideEffects
- Well tolerated with an incidence of adverse reactions similar to placebo
- Adverse reactions not dose related
- Common adverse reactions include dizziness, back pain, diarrhea, headache, hyperglycemia, and rhinitis
PregnancyLactation
Discontinue if pregnancy is detected. Can cause injury to the developing fetus. Potential excretion in human milk.
PrecautionsWarnings
Inhibiting the renin-angiotensin-aldosterone system may lead to changes in renal function. Oliguria, azotemia, acute renal failure, and death have been associated with treatment.
OverdoseEffects
- Hypotension
- Tachycardia
- Bradycardia if parasympathetic stimulation occurs
TherapeuticClass
Angiotensin II receptor blocker
StorageConditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of the reach of children
ChemicalStructure
Molecular Formula: C29H30N6O6
CommonQuestions
- Average time taken to reach peak effect is around 1 day to 1 week
- Frequency of use is generally once or twice a day
- Oral consumption advised
- Stored at room temperature, away from heat and direct light
- Quick tips for usage and potential side effects