Laxicon 20 mg+50 mg (Tablet)

Unit Price: ৳ 6.00 (30's pack: ৳ 180.00)

Medicine Details

Category	Details
Generic	Furosemide spironolactone
Company	The white horse pharmaceuticals ltd

Indications

Essential hypertension
Chronic congestive heart failure
Hepatic cirrhosis
Abdominal cavity fluid collection (ascites)
Excess fluid retention (edema)
Hyperaldosteronism
Resistant edema

Pharmacology

Spironolactone and Furosemide have complementary mechanisms and sites of action, producing additive or synergistic diuretic effect.

Dosage & Administration

Furosemide 20mg & spironolactone 50mg: 1-4 tablets daily
Furosemide 40mg & spironolactone 50mg: 1-2 tablets daily
Not suitable for children
Elderly may excrete slowly

Interaction

Increased risk of hyperkalemia with ACE inhibitors or potassium salts. Increased levels of cardiac glycosides with digoxin. Corticosteroids may cause hypokalemia. Reduction of effects with indomethacin and NSAIDs. Increase in ototoxicity with aminoglycoside antibiotics. Reduction of effects with sucralfate.

Contraindications

Anuria
Acute renal insufficiency
Severe impairment of renal function
Hyperkalaemia
Addison's disease
Hypersensitivity

Side Effects

Headache
Drowsiness
Gastrointestinal distress
Ataxia
Mental confusion
Skin rashes
Gynaecomastia
Breast enlargement
Hirsutism
Deepening of the voice
Menstrual irregularities
Impotence
Hyponatremia
Hyperkalemia
Dehydration
Reduction in blood volume
Cardiac arrhythmias

Pregnancy & Lactation

Consideration of risks versus benefits in pregnant and lactating women, potential fetal abnormalities, metabolites detected in breast milk.

Precautions & Warnings

Caution in patients liable to electrolyte deficiency
Caution in diabetes
Caution in enlarged prostate
Caution in hypotension
Caution in hypovolemia