Metfar 500 mg (Tablet)
Unit Price: ৳ 4.50 (50's pack: ৳ 225.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | The white horse pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- In adults and children from 10 years of age and adolescents
- Reduction of diabetic complications in overweight patients
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Maximum recommended daily doses
- Immediate release and extended release tablet options
- Dosage adjustments for adults and children
- Special dosage considerations for renal impaired patients
Interaction
- No chronic co-administration information with Furosemide
- Enhanced absorption with Nifedipine
- Potential interaction with cationic drugs and certain medications causing hyperglycemia
Contraindications
- Hypersensitivity to active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Conditions altering renal function
- Acute or chronic diseases causing tissue hypoxia
Side Effects
- Blood and lymphatic system disorders
- Metabolism and nutrition disorders
- Nervous system disorders
- Gastrointestinal disorders
- Hepatobiliary disorders
- Skin and subcutaneous tissue disorders
Pregnancy & Lactation
- Increased risk of congenital abnormalities and perinatal mortality in uncontrolled diabetes during pregnancy
- Excretion into human breast milk
- Limited data on breastfeeding during metformin treatment
Precautions & Warnings
- Substantial excretion by the kidney
- Lowering of vitamin B12 levels
- Increased risk of hypoglycemia
- Monitoring of renal function and Vitamin B-12 levels
- Caution in combined therapy with sulphonylurea
- Interaction with anticoagulants
Use in Special Populations
- Adjustment of dosage based on renal function in elderly subjects
- Caution in pediatric population, especially children aged between 10 and 12 years
- Regular assessment of renal function
- Special caution in situations where renal function may become impaired
Overdose Effects
- Lactic acidosis as a medical emergency
- Treatment with hemodialysis
Therapeutic Class
- Biguanides
Storage Conditions
- Temperature and light protection
- Keep out of the reach of children