Mefotrix DS 500 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Mefenamic acid |
| Company | The white horse pharmaceuticals ltd |
Indications
- Fever
- Toothache
- Headache
- Migraine
- Primary dysmenorrhoea
- Menorrhagia
- Mild to moderate pain in rheumatoid arthritis and osteoarthritis
- Traumatic pain
- Low-back pain
- Juvenile chronic arthritis in children, etc.
Pharmacology
Contains Mefenamic Acid which is a nonsteroidal agent with demonstrated analgesic, anti-inflammatory and antipyretic activity due to its dual action on prostaglandins. It inhibits the enzymes of prostaglandin synthetase and also antagonizes the actions of prostaglandin at the receptor sites.
Dosage & Administration
- Adult:
- 500 mg dose should be given to adults up to three times (1.5 gm total) per day with meals
- The dosage may be reduced to 1 tablet (250 mg) three times daily
- In case of menorrhagia: 500 mg three times daily with meals and from the onset of menses and continued according to the judgment of the physician.
- Children:
- 6 months to 1 year: 5 ml three times/day
- 2-4 years: 10 ml three times/day
- 5-8 years: 10 ml four times/day
- 9-12 years: 15 ml four times/day
- Treatment duration: Should not be continued for more than 7 days except on the advice of a physician.
Interaction
- Aspirin: Concomitant administration of Mefotrix DS and Aspirin is not generally recommended because of the potential of increased adverse effects
- Warfarin: Mefotrix DS can inhibit platelet aggregation and may prolong the prothrombin time in patients on warfarin therapy
Contraindications
Known hypersensitivity to Mefenamic Acid, peptic ulcer, inflammatory bowel diseases, hepatic or renal impairment. Also contraindicated in patients whom aspirin and/or other NSAID's have induced symptoms of bronchospasm, skin rashes.
Side Effects
- Gastrointestinal: abdominal pain, constipation, diarrhea, dyspepsia, flatulence, nausea, GI ulcers, vomiting
- Dizziness
- Abnormal renal function
- Pruritus
- Rashes
Pregnancy & Lactation
Safety not established on reproductive capacity and pregnancy. Use in women of childbearing potential and during pregnancy only when potential benefits outweigh potential risks. Mefenamic acid should not be taken by nursing mothers because of its effects on the infant's cardiovascular system.
Precautions & Warnings
Administer with caution in allergic diseases especially in asthma. Treatment should be withdrawn in case of diarrhea, rashes, cholestatic jaundice, thrombocytopenia, haemolytic anemia.
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
Keep away from light, store in a cool and dry place. Keep out of reach of children