Paracet Plus 500 mg+65 mg (Tablet)

Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)

Medicine Details

Indications

  • Headache
  • Migraine
  • Toothache
  • Neuralgia
  • Feverishness
  • Period pain
  • Sore throat
  • Backache
  • Reduce temperature
  • Aches and pain of colds and flu

Pharmacology

  • Combination of Paracetamol and Caffeine
  • Analgesic and antipyretic properties of Paracetamol
  • Weak anti-inflammatory activity of Paracetamol
  • Caffeine increases solubility and transmembrane permeation of Paracetamol
  • Caffeine raises pain threshold and tolerance
  • Caffeine raises vessel tone in the brain

Dosage & Administration

  • Adult dose: 1-2 tablets every 4-6 hours
  • Maximum dose: 8 tablets daily
  • Child dose: Not recommended for children below 12 years

Interaction

  • May reduce serum levels with anticonvulsants
  • May enhance the anticoagulant effect of warfarin
  • Accelerated absorption with metoclopramide and domperidone
  • May increase serum levels with probenecid
  • May increase serum levels of chloramphenicol
  • May reduce absorption with colestyramine
  • May cause severe hypothermia with phenothiazine

Contraindications

  • Severe renal function impairment
  • Hepatic disease (Viral Hepatitis)
  • Known hypersensitivity to paracetamol or caffeine

Side Effects

  • Mild side effects of paracetamol
  • Haematological reactions
  • Pancreatitis
  • Skin rashes
  • Allergic reactions

Pregnancy & Lactation

Consultation before taking, safe while breastfeeding

Precautions & Warnings

  • Cautious use in hepatic or renal failure patients
  • Cautious use in patients taking other hepatotoxic medication
  • Avoid prolonged use without consulting a physician

Overdose Effects

  • Pallor
  • Nausea
  • Vomiting
  • Anorexia
  • Abdominal pain
  • Liver damage after 12 to 40 hours
  • Abnormalities of glucose metabolism
  • Metabolic acidosis

Therapeutic Class

Non opioid analgesics

Storage Conditions

Cool and dry place, protect from light and moisture, keep out of reach of children

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