Bioxim DS 200 mg/5 ml (Powder for Suspension)

50 ml bottle: ৳ 280.00

Medicine Details

Title and Categories

  • Bioxim DS 200 mg/5 ml Suspension
  • Medicine
  • Antibiotic

Indications

  • Treats acute infections caused by susceptible microorganisms
  • Effective against a wide variety of Gram-positive and Gram-negative organisms
  • Marked activity in Upper Respiratory Tract Infections (URTI) and Lower Respiratory Tract Infections
  • Clinical efficacy demonstrated in infections caused by specific pathogens

Pharmacology

  • Third generation semisynthetic cephalosporin antibiotic
  • Bactericidal against a broad spectrum of gram-positive and gram-negative bacteria
  • Interferes with bacterial cell wall synthesis
  • High stability in the presence of Beta-lactamase enzyme
  • About 40% to 50% absorption, irrespective of food intake

Dosage & Administration

  • Usual course of treatment is 7 days, can be extended up to 14 days if required
  • Adult dosage ranges from 200-400 mg daily based on infection severity
  • Dosage adjustments for children based on age and weight
  • Special dosage instructions for typhoid treatment and renal impairment

Interaction

  • Potential for increases in prothrombin times when used with anticoagulant therapy

Contraindications

  • Contraindicated in patients with known hypersensitivity to cephalosporin antibiotics

Side Effects

  • Mild and self-limiting adverse reactions observed in clinical trials
  • Frequent gastrointestinal disturbances including diarrhea and stool changes
  • Other less frequent side effects include nausea, abdominal pain, headache, dizziness, hypersensitivity reactions, hematological and clinical chemistry abnormalities

Pregnancy & Lactation

  • Limited data on use in pregnant women
  • Caution advised for use during pregnancy and lactation due to potential risks

Precautions & Warnings

  • Use with caution in patients with known hypersensitivity to other drugs
  • Potential cross-allergenicity between penicillins and cephalosporins
  • Considerations for use in patients with markedly impaired renal function
  • Altered normal flora of the colon may lead to antibiotic-associated diarrhea
  • Not recommended for use in pregnancy or nursing mothers unless essential

Overdose Effects

  • Gastric lavage may be indicated in case of overdose
  • No specific antidote available
  • Adverse reactions in healthy volunteers at high doses were consistent with recommended doses

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store below 30°C temperature, protected from light & moisture
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15N5O7S2
  • Chemical Structure Image provided

Common Questions

  • What is Bioxim DS 200 mg/5 ml Syrup?
  • Uses of Bioxim DS 200 mg/5 ml Syrup
  • Side Effects of Bioxim DS 200 mg/5 ml Syrup
  • Instructions for storage and disposal of Bioxim DS 200 mg/5 ml Syrup
  • Suitability of Bioxim DS 200 mg/5 ml Syrup for treating specific conditions like cold and flu, diarrhoea, etc.
  • Special dietary instructions
  • Interaction with other medications like acetaminophen, contraception, etc.
  • Onset of action and course of treatment
  • Guidance for persistent symptoms and quick tips for usage

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