Cefone 250 mg/vial (IM Injection)

250 mg vial: ৳ 90.28

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity
  • Interference with bacterial cell wall synthesis
  • Stability in the presence of beta lactamases
  • Long plasma elimination half-life
  • Non-metabolized in the body
  • Excretion in urine and bile
  • High protein binding

Dosage

  • Usual adult dose: 1 to 2 gm by IV or IM once a day
  • Maximum adult dose: 4 gm/day
  • Usual pediatric dose: 50 to 75 mg/kg IV or IM once a day
  • Maximum pediatric dose: 2 gm/day
  • Duration of therapy: 4 to 14 days

Administration

  • Preparation for intramuscular and intravenous injections
  • Recommended solutions for injections
  • Administration over 2-4 minutes for IM or IV injection
  • Tubing infusion over 30 minutes
  • Patient tolerance test before treatment

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis

Pregnancy & Lactation

  • Unsafe for use in pregnancy unless absolutely indicated
  • Caution in lactating mothers

Precautions & Warnings

  • Risk of anaphylactic shock
  • Gallbladder conditions
  • Blood picture check during prolonged treatment

Use in Special Populations

  • Unsafe for neonates if premature or newborn (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in cool, dry place below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

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