Cefone 500 mg/vial (IM Injection)
500 mg vial: ৳ 120.37
Medicine Details
Category | Details |
---|---|
Generic | Ceftriaxone sodium |
Company | Sharif pharmaceuticals ltd |
Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum antibiotic
- Bactericidal activity
- Gram-positive and Gram-negative activity
- Interferes with bacterial cell wall synthesis
- Long plasma elimination half-life (6-9 hours)
- Not metabolized in the body
- Highly protein bound (95%)
Dosage
- Usual adult dose: 1 to 2 gm by intravenous or intramuscular administration
- Usual pediatric dose: 50 to 75 mg/kg intravenous or intramuscular administration
- Maximum dose for various infections
- Duration of therapy: 4 to 14 days
Administration
- Preparation of solutions for intramuscular/intravenous injections
- Different concentrations for intramuscular and intravenous injections
- Administered over 2-4 minutes for intramuscular or intravenous injection or tubing infusion over 30 minutes
- Recommendation for patient tolerance test
Interaction
- No reported drug interactions
Contraindications
- Not to be given to patients with history of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastrointestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Rare local phlebitis following intravenous administration
Pregnancy & Lactation
- Safety not established in human pregnancy
- Caution in lactating mothers
Precautions & Warnings
- Potential for anaphylactic shock
- Shadow suggesting sludge in gallbladder
- Blood picture check during prolonged treatment
Use in Special Populations
- Avoid use in neonates if premature and newborn up to 28 days
Overdose Effects
- No specific antidote
- Symptomatic treatment
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store vial in cool, dry place (below 30°C)
- Keep away from light and moisture
- Keep out of reach of children