Cefone 500 mg/vial (IM Injection)

500 mg vial: ৳ 120.37

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibiotic
  • Bactericidal activity
  • Gram-positive and Gram-negative activity
  • Interferes with bacterial cell wall synthesis
  • Long plasma elimination half-life (6-9 hours)
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Usual adult dose: 1 to 2 gm by intravenous or intramuscular administration
  • Usual pediatric dose: 50 to 75 mg/kg intravenous or intramuscular administration
  • Maximum dose for various infections
  • Duration of therapy: 4 to 14 days

Administration

  • Preparation of solutions for intramuscular/intravenous injections
  • Different concentrations for intramuscular and intravenous injections
  • Administered over 2-4 minutes for intramuscular or intravenous injection or tubing infusion over 30 minutes
  • Recommendation for patient tolerance test

Interaction

  • No reported drug interactions

Contraindications

  • Not to be given to patients with history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Rare local phlebitis following intravenous administration

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution in lactating mothers

Precautions & Warnings

  • Potential for anaphylactic shock
  • Shadow suggesting sludge in gallbladder
  • Blood picture check during prolonged treatment

Use in Special Populations

  • Avoid use in neonates if premature and newborn up to 28 days

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store vial in cool, dry place (below 30°C)
  • Keep away from light and moisture
  • Keep out of reach of children

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