Fixen 180 mg (Tablet)
Unit Price: ৳ 10.00 (2 x 10: ৳ 200.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fexofenadine hydrochloride |
| Company | Sharif pharmaceuticals ltd |
| Also available as |
Indications
- Relief of seasonal and perennial allergic rhinitis symptoms
- Relief of chronic idiopathic urticaria symptoms
Pharmacology
- Fexofenadine is an inverse agonist of the H1 receptor
- Potent and selective affinity for H1 receptors
- No evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
Dosage & Administration
- Adult dosage: 60 mg twice daily or 120 mg/180 mg once daily
- Pediatric dosage: varies based on age and condition
Interaction
- No hepatic biotransformation
- Coadministration with erythromycin or ketoconazole may increase fexofenadine level in plasma
- No interaction with omeprazole, but interaction with antacids containing aluminum and magnesium hydroxide
Contraindications
- Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients
Side Effects
- Common: headache, drowsiness, dizziness, nausea, fatigue
- Uncommon: insomnia, tachycardia, diarrhea, rash, urticaria, pruritus
- Rare: hypersensitivity reactions with manifestations such as angioedema, chest tightness, dyspnoea, flushing and systemic anaphylaxis
Pregnancy & Lactation
- Limited data on use in pregnant women
- Not recommended during breastfeeding
Precautions & Warnings
- Limited data in older people and renally or hepatically impaired patients
- Patients with a history of or ongoing cardiovascular disease should be warned
- Unlikely to produce significant effects on driving or use of machines
Use in Special Populations
- Altered pharmacokinetics in patients with renal impairment
- No substantial effect on pharmacokinetics in moderate to severe hepatic disease
- Adverse events similar in elderly patients
Overdose Effects
- Reported effects include dizziness, drowsiness, fatigue, and dry mouth
- Maximum tolerated dose not established
- Standard measures for removal of unabsorbed product recommended
Therapeutic Class
Non-sedating antihistamines
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C32H39NO4
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-468-fexofenadine-hydrochloride-chemical-structure-HrM3XW8ofnGVhLdcBRox.svg
Common Questions about Fixen 180 mg Tablet
- What is Fixen 180 mg Tablet?: An antihistamine that blocks histamine during allergic reactions
- Uses: Treatment of allergic rhinitis and urticaria
- Side Effects: Vomiting, headache, coughing, diarrhea, hives, swelling, pain, etc.
- Instructions for storage and disposal: Keep in cool, dry place and out of reach of children and pets
- Can cause sleepiness: Yes, it can cause sleepiness
- Overdose risk: Avoid overdose to prevent adverse reactions
- Speed of action: Starts working within 1 hour with peak benefit in 6 hours
- Relief of outdoor and indoor allergies: Helps relieve symptoms caused by various allergens
- How to cope with dizziness: Rest and caution with machinery; consult doctor if extreme dizziness
- Antacids interaction: Should not be used in combination with antacids
- Dosage instructions: Should be taken as recommended by the doctor
- Food or drink to avoid: Avoid consuming certain fruit juices while on the medication
- Heart problems risk: Exercise caution for those with heart disorders
- Quick Tips:
- An antihistaminic medication
- Less likely to cause sleepiness
- Avoid fruit juices while taking
- May cause nausea, avoid rich or spicy food
- Avoid using antacids 30 minutes before or after taking