Dialozin 5 mg (Tablet)
Unit Price: ৳ 16.00 (3 x 10: ৳ 480.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Dapagliflozin propanediol |
| Company | Jenphar bangladesh ltd |
Indications
- Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
Pharmacology
- Dapagliflozin is an inhibitor of Sodium-glucose co-transporter 2 (SGLT2)
Dosage & Administration
- Recommended starting dose of 5 mg once daily for adults
- Can be taken with or without food
- Assessment of renal function recommended prior to initiation
- Not recommended for children and adolescents under 18 years
Interaction
- May interact with diuretics, insulin, insulin secretagogues, antihypertensives, pioglitazone, agents affecting renal function, GLP-1 agonists, valsartan, rifampin, mefenamic acid
Contraindications
- Known hypersensitivity to Dapagliflozin or excipients
- Severe renal impairment, end-stage renal diseases, or patients on dialysis
Side Effects
- Hypotension
- Ketoacidosis
- Acute kidney injury
- Impairment in renal function
- Urosepsis and pyelonephritis
- Hypoglycemia with concomitant use with insulin and insulin secretagogues
- Genital mycotic infections
- Increases in low-density lipoprotein cholesterol (LDL-C)
- Nasopharyngitis
- Urinary tract infection
- Bladder cancer
Pregnancy & Lactation
- Pregnancy category C
- Should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus
- Not recommended for use during lactation
Precautions & Warnings
- Assess volume status and correct hypovolemia before initiation
- Monitor renal function during therapy
- Consider a lower dose of insulin or the insulin secretagogue to reduce the risk of hypoglycemia
- Not recommended for patients with active bladder cancer
Therapeutic Class
- Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
- Store below 30°C in a cool, dry place protected from light
- Keep away from the reach of children