Lubicon 8 mcg (Capsule)

Unit Price: ৳ 15.00 (5 x 6: ৳ 450.00)

Strip Price: ৳ 90.00

Medicine Details

Category	Details
Generic	Lubiprostone
Company	Jenphar bangladesh ltd
Also available as	Lubicon 24 mcg capsule

Indications

Irritable Bowel Syndrome with Constipation (IBS-C)
Chronic Idiopathic Constipation (CIC) in adults
Opioid-Induced Constipation (OIC) in adult patients with chronic, non-cancer pain

Pharmacology

Locally-acting chloride-channel activator, increases intestinal secretion, increases intestinal motility, activates ClC-2 chloride channels, efflux of chloride ions, efflux of sodium ions, water follows sodium into the lumen, stimulates recovery of muscosal barrier function

Dosage & Administration

Irritable Bowel Syndrome with Constipation: 8 mcg twice daily orally with food and water
Dosage in patients with hepatic impairment: Dose adjustment not required for moderately impaired hepatic function, recommended starting dose is 8 mcg once daily for severely impaired hepatic function
Chronic Idiopathic Constipation and Opioid-induced Constipation: 24 mcg twice daily orally with food and water
Dosage in patients with hepatic impairment for Chronic Idiopathic Constipation and Opioid-induced Constipation: 16 mcg twice daily for moderately impaired hepatic function, 8 mcg twice daily for severely impaired hepatic function

Interaction

Possibility of a dose-dependent decrease in efficacy in patients using diphenylheptane opioids

Contraindications

Contraindicated in patients with known or suspected mechanical gastrointestinal obstruction

Side Effects

Diarrhea
Full or bloated feeling or pressure in the stomach
Nausea
Stomach pain
Swelling of abdominal or stomach area
Dyspnea

Pregnancy & Lactation

Pregnancy category: C
Excretion in milk: Not known
Caution for nursing woman: Caution should be exercised when Lubiprostone is administered to a nursing woman

Precautions & Warnings

Nausea: Patients taking Lubicon may experience nausea. Concomitant administration of food with Lubicon may reduce symptoms of nausea
Diarrhea: Lubistone should not be prescribed to patients that have severe diarrhea
Bowel Obstruction: In patients with symptoms suggestive of mechanical gastrointestinal obstruction, perform a thorough evaluation to confirm the absence of an obstruction prior to initiating therapy with Lubicon

Overdose Effects

Nausea
Diarrhea
Vomiting
Dizziness
Headache
Abdominal pain
Flushing/hot flash
Retching
Dyspnea
Pallor
Stomach discomfort
Anorexia
Asthenia
Chest discomfort
Dry mouth
Hyperhidrosis
Syncope